9-ME-BC (9-Methyl-Beta-Carboline)
Category: nootropics
Mentions
cortxin + 9-me-bc = dopaminergic system restoration
PQQ + ubiquinol = elite preworkout
TTFD + methylated B-vitamins = ridiculous energy
dihexa + nicotine = elite writing & memory
[Reply from BasedBiohacker @BasedBiohacker - Jun 10: epitalon = amazing sleep
modafinil + bromantane = amazing focus
psilocybin + mexidol = amazing charisma
meldonium + tadalafil = amazing stamina
selank + fasopracetam = amazingly calm...]
[Image of a person walking on a glowing path at night in a field]
4:59 PM · Jun 10, 2026 · 15K Views
Compounds: cortxin, 9-ME-BC (9-methyl-beta-carboline), PQQ, ubiquinol, TTFD (thiamine tetrahydrofurfuryl disulfide), methylated B-vitamins, Dihexa, nicotine, epitalon, modafinil, bromantane, psilocybin, mexidol, meldonium, tadalafil, selank, fasopracetam
PQQ + ubiquinol = elite preworkout
TTFD + methylated B-vitamins = ridiculous energy
dihexa + nicotine = elite writing & memory
[Reply from BasedBiohacker @BasedBiohacker - Jun 10: epitalon = amazing sleep
modafinil + bromantane = amazing focus
psilocybin + mexidol = amazing charisma
meldonium + tadalafil = amazing stamina
selank + fasopracetam = amazingly calm...]
[Image of a person walking on a glowing path at night in a field]
4:59 PM · Jun 10, 2026 · 15K Views
Compounds: cortxin, 9-ME-BC (9-methyl-beta-carboline), PQQ, ubiquinol, TTFD (thiamine tetrahydrofurfuryl disulfide), methylated B-vitamins, Dihexa, nicotine, epitalon, modafinil, bromantane, psilocybin, mexidol, meldonium, tadalafil, selank, fasopracetam
BScreenshot 2026-06-17 at 21.48.33.png.txt
A TIER: 9-Me-BC: MAO-B inhibitor preventing dopamine breakdown while promoting neurogenesis and BDNF
[Also posted at https://x.com/aestheticprimal/status/2038649360976658450 — same thread]
Current Dopamine enhancement stack
extra fire to crush objectives (and actually chase the right objectives)
- 5mL Cerebrolysin (EOD)
- 2-4 IU Intranasal insulin (almost daily)
- 2g+ royal jelly (daily)
- 10-15mg 9-me-bc (daily)
below is why!👇
[reply] Cerebrolysin seems to enhance Dopaminergic transmission mainly through improving redox balance (total antioxidant capacity), and also seemingly through activation of GDNF receptor complex. Evidence on Cerebrolysin and Dopamine itself has not been studied much, but from personal experience the Dopamine baseline seems to be much much higher. when it comes to sourcing it, it's very different per region, Rupharma is decent, but even Indiamart is a better alternative.
[reply] Intranasal Insulin seems to be something very niche, until you realize that there's a tremendous amount of scientific literature on it, just go on google scholar and type in 'intranasal insulin' and you'll see. Seems to be mainly mediated through improving redox balance in the brain.
[reply] Royal Jelly does an amazing job at enhancing the burst firing of Dopaminergic neurons in the VTA (ventral tegmental area), through the connection of the VTA to the NAc (nucleus accumbens) it then enhances the desire to get stuff done.
[reply] 9-me-bc is one of the newer additions, and is perhaps the most potent tool for improving Dopaminergic transmission and getting that feeling of "I wanna get shit done today"; improves expression of enzymes required in Dopamine synthesis, improves total health of Dopaminergic neurons.
[related article] 9-me-bc - USE IT — 9-me-bc is an abbreviation for 9-methyl-beta-carboline... (see paper Polanski W et al., J Neurochem 2010, PMID 20374418)
Compounds: cerebrolysin, intranasal insulin, royal jelly, 9-me-bc (9-methyl-beta-carboline)
Current Dopamine enhancement stack
extra fire to crush objectives (and actually chase the right objectives)
- 5mL Cerebrolysin (EOD)
- 2-4 IU Intranasal insulin (almost daily)
- 2g+ royal jelly (daily)
- 10-15mg 9-me-bc (daily)
below is why!👇
[reply] Cerebrolysin seems to enhance Dopaminergic transmission mainly through improving redox balance (total antioxidant capacity), and also seemingly through activation of GDNF receptor complex. Evidence on Cerebrolysin and Dopamine itself has not been studied much, but from personal experience the Dopamine baseline seems to be much much higher. when it comes to sourcing it, it's very different per region, Rupharma is decent, but even Indiamart is a better alternative.
[reply] Intranasal Insulin seems to be something very niche, until you realize that there's a tremendous amount of scientific literature on it, just go on google scholar and type in 'intranasal insulin' and you'll see. Seems to be mainly mediated through improving redox balance in the brain.
[reply] Royal Jelly does an amazing job at enhancing the burst firing of Dopaminergic neurons in the VTA (ventral tegmental area), through the connection of the VTA to the NAc (nucleus accumbens) it then enhances the desire to get stuff done.
[reply] 9-me-bc is one of the newer additions, and is perhaps the most potent tool for improving Dopaminergic transmission and getting that feeling of "I wanna get shit done today"; improves expression of enzymes required in Dopamine synthesis, improves total health of Dopaminergic neurons.
[related article] 9-me-bc - USE IT — 9-me-bc is an abbreviation for 9-methyl-beta-carboline... (see paper Polanski W et al., J Neurochem 2010, PMID 20374418)
Compounds: cerebrolysin, intranasal insulin, royal jelly, 9-me-bc (9-methyl-beta-carboline)
9-methyl-β-carboline up-regulated tyrosine hydroxylase and dopaminergic transcription factors (Gata2/3, Creb1, Crebbp), stimulated neurite outgrowth, protected and regenerated TH+ dopaminergic neurons (LPS, rotenone models), had anti-inflammatory effects on microglia and lowered α-synuclein — a multi-mechanism anti-parkinsonian candidate. PMID 20374418.
Compounds: 9-me-bc
Compounds: 9-me-bc