Adamax (N-Acetyl Semax Amidate, adamantane)
Category: nootropics
Information Sheet
What It Is
Adamax is a potent derivative of Semax — N-Acetyl Semax with an adamantane moiety — giving better BBB penetration, longer half-life and stronger acute nootropic effect.
Mechanism & Notes
- Melanocortin receptor modulator; boosts neurogenesis via BDNF & NGF and upregulates TrkB
- Best for acute cognitive enhancement; reduces procrastination, potentiates stimulants
Mentions
I've been using the 2 strongest cognitive-enhancing peptides on the planet so you don't have to
1. P21
It's so powerful that it boosts neurogenesis in Alzheimer's brains above that of normal controls
It's a derivative of Ciliary Neurotrophic Factor (CNTF) and was developed by reverse-engineering the magic behind Cerebrolysin
(Cerebrolysin is the #1 nootropic tool of all-time)
- Unlocks peak neurogenesis (inhibits LIF)
- Potently turbocharges BDNF expression
- Best peptide for repairing brain damage
- Strong anti-Alzheimer's effect (in rats)
Here's what I noticed with P21 so far:
- Initial brain fog due to neurogenesis
- Impressive mental clarity after that
- Reduces "tip of the tongue" moments
- Next-level verbal acuity
2. Adamax
Adamax is the most potent derivative of Semax
(The time-tested nootropic peptide that's been used in Russia for 40 years)
It's essentially N-Acetyl Semax with an adamantane moiety attached
The "N-Acetyl" enhances BBB penetration while the adamantane modification increases its half-life & potency
- Melanocortin receptor modulator
- Boosts neurogenesis via BDNF & NGF
- Upregulates BDNF's receptor (TrkB)
- Best for acute cognitive enhancement
Here's what I noticed with Adamax so far:
- Noticeably reduces procrastination
- Great for tweet ideation & writing
- Makes stimulants stronger
- Colors are more vivid
Important note- both are relatively experimental tools and should be used with caution
TLDR?
P21 = Heavy duty brain repair
Adamax = Heavy duty acute nootropic
[reply] 2 nasal sprays in morning, have done up to 4
[reply] Highly recommend checking this paper out on P21
Compounds: P21, Adamax, Semax, Cerebrolysin
1. P21
It's so powerful that it boosts neurogenesis in Alzheimer's brains above that of normal controls
It's a derivative of Ciliary Neurotrophic Factor (CNTF) and was developed by reverse-engineering the magic behind Cerebrolysin
(Cerebrolysin is the #1 nootropic tool of all-time)
- Unlocks peak neurogenesis (inhibits LIF)
- Potently turbocharges BDNF expression
- Best peptide for repairing brain damage
- Strong anti-Alzheimer's effect (in rats)
Here's what I noticed with P21 so far:
- Initial brain fog due to neurogenesis
- Impressive mental clarity after that
- Reduces "tip of the tongue" moments
- Next-level verbal acuity
2. Adamax
Adamax is the most potent derivative of Semax
(The time-tested nootropic peptide that's been used in Russia for 40 years)
It's essentially N-Acetyl Semax with an adamantane moiety attached
The "N-Acetyl" enhances BBB penetration while the adamantane modification increases its half-life & potency
- Melanocortin receptor modulator
- Boosts neurogenesis via BDNF & NGF
- Upregulates BDNF's receptor (TrkB)
- Best for acute cognitive enhancement
Here's what I noticed with Adamax so far:
- Noticeably reduces procrastination
- Great for tweet ideation & writing
- Makes stimulants stronger
- Colors are more vivid
Important note- both are relatively experimental tools and should be used with caution
TLDR?
P21 = Heavy duty brain repair
Adamax = Heavy duty acute nootropic
[reply] 2 nasal sprays in morning, have done up to 4
[reply] Highly recommend checking this paper out on P21
Compounds: P21, Adamax, Semax, Cerebrolysin