Butyrate / Sodium Butyrate
Category: other
Mentions
MScreenshot 2026-06-16 at 19.33.41.png.txt
https://x.com/doctormorphh/s... (MORE.HAIR DM for access to pres... @monkeywith... Jun 15)
Vitamin E is very underrated for gut health by increasing gut barrier integrity and SCFAs like butyrate.
[Includes text from a research abstract about vitamin E treatment increasing relative abundance of SCFA-producing bacteria including Akkermansia (butyrate producer), Bifidobacterium (acetate and propionate producer), Lachnospira (butyrate producer). Also references TEER (transepithelial electrical resistance).]
Compounds: vitamin E, butyrate, SCFAs (short-chain fatty acids)
Vitamin E is very underrated for gut health by increasing gut barrier integrity and SCFAs like butyrate.
[Includes text from a research abstract about vitamin E treatment increasing relative abundance of SCFA-producing bacteria including Akkermansia (butyrate producer), Bifidobacterium (acetate and propionate producer), Lachnospira (butyrate producer). Also references TEER (transepithelial electrical resistance).]
Compounds: vitamin E, butyrate, SCFAs (short-chain fatty acids)
Sodium butyrate raises testosterone via the LH/cAMP/PKA pathway in the Leydig cells of the testes.
By activating this pathway, butyrate upregulates the LH receptor, StAR, and CYP11A1 (the rate-limiting enzyme that converts cholesterol into pregnenolone).
Two studies:
1) Hyperuricemia model
Male mice with high uric acid were given 300 mg/kg/day of sodium butyrate for three weeks. It increased serum testosterone, sperm count, and motility, and activated the LH/cAMP/PKA pathway in their Leydig cells.
PMID: 40295597
2) Obesity model
Male mice made obese on a high-fat diet were given butyrate (5% of the diet) for 12 weeks. It increased testicular testosterone and restored sperm count and morphology while improving motility, by normalizing the testicular steroid-biosynthesis pathway.
PMID: 40226081
[Image shows a sodium butyrate supplement bottle and a testosterone level graph]
2:04 PM · Jun 10, 2026 · 1,441 Views
Compounds: sodium butyrate, pregnenolone, cholesterol
By activating this pathway, butyrate upregulates the LH receptor, StAR, and CYP11A1 (the rate-limiting enzyme that converts cholesterol into pregnenolone).
Two studies:
1) Hyperuricemia model
Male mice with high uric acid were given 300 mg/kg/day of sodium butyrate for three weeks. It increased serum testosterone, sperm count, and motility, and activated the LH/cAMP/PKA pathway in their Leydig cells.
PMID: 40295597
2) Obesity model
Male mice made obese on a high-fat diet were given butyrate (5% of the diet) for 12 weeks. It increased testicular testosterone and restored sperm count and morphology while improving motility, by normalizing the testicular steroid-biosynthesis pathway.
PMID: 40226081
[Image shows a sodium butyrate supplement bottle and a testosterone level graph]
2:04 PM · Jun 10, 2026 · 1,441 Views
Compounds: sodium butyrate, pregnenolone, cholesterol
Want a healthy gut barrier integrity? One needs to protect & regulate the gut sealing protein: Claudin-3.
Low Claudin-3 = compromised barrier = higher risk of systemic inflammation, autoimmunity, and neurological diseases. Compounds that preserve Claudin-3:
- Vitamin D
- Zinc L-Carnosine
- Lactoferrin / Colostrum
- L-Glutamine
- Butyrate / Tributyrin
- Gelatin / Bone Broth
- Quercetin
- Curcumin
- Apigenin
- EGCG
12:58 AM · Apr 23, 2025 · 33.8K Views
[Reply from Andra @BioavailableNd - Apr 23, 2025: It could be as simple as daily sunlight, a few glasses of raw milk for lactoferrin, bone broth with onions peels for quercetin and gelatine, a few cups of green tea or chamomile tea a week and cooking with lots of culinary herbs and spices. Or supplements like Gut Health Combo by @objectivenutri if needed for acute issues.]
[Reply from DOMO @BOOMHealth - Apr 23, 2025: Excellent list, Andra. Just to add a quantum biology layer: Claudin-3 isn't only influenced by nutrients, it's regulated by mitochondrial redox rhythm, circadian gene expression, and photonic signaling.
- Melatonin (synthesized locally in GI tract) preserves Claudin-3 via...]
Compounds: vitamin D, zinc L-carnosine, lactoferrin, colostrum, L-glutamine, butyrate, tributyrin, gelatin, quercetin, curcumin, apigenin, EGCG, melatonin
Low Claudin-3 = compromised barrier = higher risk of systemic inflammation, autoimmunity, and neurological diseases. Compounds that preserve Claudin-3:
- Vitamin D
- Zinc L-Carnosine
- Lactoferrin / Colostrum
- L-Glutamine
- Butyrate / Tributyrin
- Gelatin / Bone Broth
- Quercetin
- Curcumin
- Apigenin
- EGCG
12:58 AM · Apr 23, 2025 · 33.8K Views
[Reply from Andra @BioavailableNd - Apr 23, 2025: It could be as simple as daily sunlight, a few glasses of raw milk for lactoferrin, bone broth with onions peels for quercetin and gelatine, a few cups of green tea or chamomile tea a week and cooking with lots of culinary herbs and spices. Or supplements like Gut Health Combo by @objectivenutri if needed for acute issues.]
[Reply from DOMO @BOOMHealth - Apr 23, 2025: Excellent list, Andra. Just to add a quantum biology layer: Claudin-3 isn't only influenced by nutrients, it's regulated by mitochondrial redox rhythm, circadian gene expression, and photonic signaling.
- Melatonin (synthesized locally in GI tract) preserves Claudin-3 via...]
Compounds: vitamin D, zinc L-carnosine, lactoferrin, colostrum, L-glutamine, butyrate, tributyrin, gelatin, quercetin, curcumin, apigenin, EGCG, melatonin
Every supplement I have utilised to heal my gut to date:
- S. Boulardii
- Black seed oil
- Meriva Curcumin
- Lactoferrin
- Boswellia
- Quercetin
- Coconut oil
- Bismuth
- BPC157
- GHKcu
- Larazotide
- Butyrate
- Zinc L carnosine
- Spore based probiotics
- Beta caryphollene
- Lysozyme
- TUDCA
- Taurine
- Glycine
- Gelatine
- Magnesium
[Image shows lactoferrin powder bag, glycine powder bag, and other supplements]
7:12 PM · Jun 9, 2026 · 41.5K Views
Compounds: S. Boulardii, black seed oil, curcumin (Meriva), lactoferrin, boswellia, quercetin, coconut oil, bismuth, BPC-157, GHK-Cu, larazotide, butyrate, zinc L-carnosine, beta-caryophyllene, lysozyme, TUDCA, taurine, glycine, gelatine, magnesium
- S. Boulardii
- Black seed oil
- Meriva Curcumin
- Lactoferrin
- Boswellia
- Quercetin
- Coconut oil
- Bismuth
- BPC157
- GHKcu
- Larazotide
- Butyrate
- Zinc L carnosine
- Spore based probiotics
- Beta caryphollene
- Lysozyme
- TUDCA
- Taurine
- Glycine
- Gelatine
- Magnesium
[Image shows lactoferrin powder bag, glycine powder bag, and other supplements]
7:12 PM · Jun 9, 2026 · 41.5K Views
Compounds: S. Boulardii, black seed oil, curcumin (Meriva), lactoferrin, boswellia, quercetin, coconut oil, bismuth, BPC-157, GHK-Cu, larazotide, butyrate, zinc L-carnosine, beta-caryophyllene, lysozyme, TUDCA, taurine, glycine, gelatine, magnesium
GScreenshot 2026-06-16 at 20.12.27.png.txt
https://x.com/FarvingCo/status/1912858935250068213 (approx.)
These are the best supplements:
- Gelatin / glycine
- Glutamine
- Lactoferrin
- Mastic gum
- Sodium Butyrate
- Zinc Carnosine
If you want to experiment with peptides, BPC-157 is insane for gut health
Cut out all irritating foods, eat only nutrient dense whole foods:
- Dairy
- Meat
- Gelatin/bone broth
- Eggs
- Organs (liver, heart)
- Oysters
- Shilajit
- Bee pollen
- Dark chocolate
- Royal jelly
- Colostrum powder
Hope this helps.
2:23 PM · Apr 11, 2025 · 204 Views
Compounds: gelatin, glycine, glutamine, lactoferrin, mastic gum, sodium butyrate, zinc carnosine, BPC-157, shilajit, bee pollen, royal jelly, colostrum
These are the best supplements:
- Gelatin / glycine
- Glutamine
- Lactoferrin
- Mastic gum
- Sodium Butyrate
- Zinc Carnosine
If you want to experiment with peptides, BPC-157 is insane for gut health
Cut out all irritating foods, eat only nutrient dense whole foods:
- Dairy
- Meat
- Gelatin/bone broth
- Eggs
- Organs (liver, heart)
- Oysters
- Shilajit
- Bee pollen
- Dark chocolate
- Royal jelly
- Colostrum powder
Hope this helps.
2:23 PM · Apr 11, 2025 · 204 Views
Compounds: gelatin, glycine, glutamine, lactoferrin, mastic gum, sodium butyrate, zinc carnosine, BPC-157, shilajit, bee pollen, royal jelly, colostrum
Want a healthy gut barrier integrity? One needs to protect & regulate the gut sealing protein: Claudin-3.
Low Claudin-3 = compromised barrier = higher risk of systemic inflammation, autoimmunity, and neurological diseases. Compounds that preserve Claudin-3:
- Vitamin D
- Zinc L-Carnosine
- Lactoferrin / Colostrum
- L-Glutamine
- Butyrate / Tributyrin
- Gelatin / Bone Broth
- Quercetin
- Curcumin
- Apigenin
- EGCG
12:56 AM · Apr 23, 2025 · 32.8K Views
[Reply from Andra @BioavailableNd - Apr 23, 2025: It could be as simple as daily sunlight, a few glasses of raw milk for lactoferrin, bone broth with onions peels for quercetin and gelatine, a few cups of green tea or chamomile tea a week and cooking with lots of culinary herbs and spices. Or supplements like Gut Health Combo by @objectivenutri if needed for acute issues.]
Compounds: vitamin D, zinc L-carnosine, lactoferrin, colostrum, L-glutamine, butyrate, tributyrin, gelatin, quercetin, curcumin, apigenin, EGCG
Low Claudin-3 = compromised barrier = higher risk of systemic inflammation, autoimmunity, and neurological diseases. Compounds that preserve Claudin-3:
- Vitamin D
- Zinc L-Carnosine
- Lactoferrin / Colostrum
- L-Glutamine
- Butyrate / Tributyrin
- Gelatin / Bone Broth
- Quercetin
- Curcumin
- Apigenin
- EGCG
12:56 AM · Apr 23, 2025 · 32.8K Views
[Reply from Andra @BioavailableNd - Apr 23, 2025: It could be as simple as daily sunlight, a few glasses of raw milk for lactoferrin, bone broth with onions peels for quercetin and gelatine, a few cups of green tea or chamomile tea a week and cooking with lots of culinary herbs and spices. Or supplements like Gut Health Combo by @objectivenutri if needed for acute issues.]
Compounds: vitamin D, zinc L-carnosine, lactoferrin, colostrum, L-glutamine, butyrate, tributyrin, gelatin, quercetin, curcumin, apigenin, EGCG
Every supplement I have utilised to heal my gut to date:
- S. Boulardii
- Black seed oil
- Meriva Curcumin
- Lactoferrin
- Boswellia
- Quercetin
- Coconut oil
- Bismuth
- BPC157
- GHKcu
- Larazotide
- Butyrate
- Zinc L carnosine
- Spore based probiotics
- Beta caryphollene
- Lysozyme
- TUDCA
- Taurine
- Glycine
- Gelatine
- Magnesium
[Image shows supplement packaging for Lactoferrin and GLYCINE 100g]
7:12 PM · Jun 9, 2026 · 41.5K Views
Compounds: S. Boulardii, black seed oil, curcumin (Meriva), lactoferrin, boswellia, quercetin, coconut oil, bismuth, BPC-157, GHK-Cu, larazotide, butyrate, zinc L-carnosine, beta-caryophyllene, lysozyme, TUDCA, taurine, glycine, gelatine, magnesium
- S. Boulardii
- Black seed oil
- Meriva Curcumin
- Lactoferrin
- Boswellia
- Quercetin
- Coconut oil
- Bismuth
- BPC157
- GHKcu
- Larazotide
- Butyrate
- Zinc L carnosine
- Spore based probiotics
- Beta caryphollene
- Lysozyme
- TUDCA
- Taurine
- Glycine
- Gelatine
- Magnesium
[Image shows supplement packaging for Lactoferrin and GLYCINE 100g]
7:12 PM · Jun 9, 2026 · 41.5K Views
Compounds: S. Boulardii, black seed oil, curcumin (Meriva), lactoferrin, boswellia, quercetin, coconut oil, bismuth, BPC-157, GHK-Cu, larazotide, butyrate, zinc L-carnosine, beta-caryophyllene, lysozyme, TUDCA, taurine, glycine, gelatine, magnesium