Desoxyn (Methamphetamine)
Category: stimulants
Information Sheet
What It Is
Desoxyn is pharmaceutical methamphetamine; cited as an example of a heavy stimulant whose neurotoxicity needs aggressive neuroprotection.
Mechanism & Notes
- Potent releasing agent for dopamine/noradrenaline
- Flagged for the neurotoxicity that drives the neuroprotection discussion
Mentions
Quite liked the guys Nootropic stack I read about a while ago:
- Meldonium
- Emoxypine Succinate (Mexidol)
- Cerebrolysin
- Noopept
- Alpha-GPC
- Memantine
But no clue why someone would run stimulants like Adderall, Desoxyn and God knows what else, and expect all the neurotoxicity to be mitigated with Mexidol, S-Ketamine and Cerebrolysin, more neuroprotection is needed.
Would add:
- HDACi's like Crebinostat or Varinostat (tolerance reversal)
- NACET as superior version of NAC (neuroprotection)
- Bromantane + L-Tyrosine/NALT on hand to replenish Dopamine stores asap and an additional GDNF boost
- Absolute Magnesium megadoses, 1g elemental (Threonate, Glycinate, Chloride etc.)
[reply] not a fan of things that rapidly induce neuroplasticity because they very often mess up top-down control from the prefrontal cortex, it's why i am a bit cautious of Dihexa, low dose probably different tho. Cortexin is nice, but I'd say Pinealon is even more potent for cognition
[reply] i think mexidol, cerebrolysin and perhaps some pinealon would work great
Compounds: meldonium, mexidol (emoxypine succinate), cerebrolysin, noopept, alpha-GPC, memantine, Adderall, Desoxyn, S-ketamine, crebinostat, vorinostat (varinostat), NACET, bromantane, L-tyrosine/NALT, dihexa, cortexin, pinealon, magnesium
- Meldonium
- Emoxypine Succinate (Mexidol)
- Cerebrolysin
- Noopept
- Alpha-GPC
- Memantine
But no clue why someone would run stimulants like Adderall, Desoxyn and God knows what else, and expect all the neurotoxicity to be mitigated with Mexidol, S-Ketamine and Cerebrolysin, more neuroprotection is needed.
Would add:
- HDACi's like Crebinostat or Varinostat (tolerance reversal)
- NACET as superior version of NAC (neuroprotection)
- Bromantane + L-Tyrosine/NALT on hand to replenish Dopamine stores asap and an additional GDNF boost
- Absolute Magnesium megadoses, 1g elemental (Threonate, Glycinate, Chloride etc.)
[reply] not a fan of things that rapidly induce neuroplasticity because they very often mess up top-down control from the prefrontal cortex, it's why i am a bit cautious of Dihexa, low dose probably different tho. Cortexin is nice, but I'd say Pinealon is even more potent for cognition
[reply] i think mexidol, cerebrolysin and perhaps some pinealon would work great
Compounds: meldonium, mexidol (emoxypine succinate), cerebrolysin, noopept, alpha-GPC, memantine, Adderall, Desoxyn, S-ketamine, crebinostat, vorinostat (varinostat), NACET, bromantane, L-tyrosine/NALT, dihexa, cortexin, pinealon, magnesium