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DMSO (Dimethyl Sulfoxide)

Category: other

Information Sheet

What It Is

DMSO is a powerful penetration enhancer and solvent used to drive topical actives (e.g. GHK-Cu) through the stratum corneum.

Mechanism & Notes

  • Aggressive transdermal penetration enhancer ('a sledgehammer')
  • Carries polar/hydrophilic molecules like copper-bound GHK-Cu across intact skin

Mentions

RRandy Cole (@RegenRandy)view on X ↗
Please don't do this. Reconstituted GHK-Cu in bac water has awful skin penetration, because it's highly polar, hydrophilic, and copper-bound - passive diffusion through intact skin is pretty much impossible.
Cosmetic GHK-Cu products are formulated with penetration enhancers and optimized vehicles for a reason. Repeatedly wiping benzyl alcohol on your face isn't a skincare hack - at least use sterile water.
[reply] DMSO will help, but it's a sledgehammer - a very aggressive penetration enhancer.
I buy my GHK-Cu serum from @sevo_skincare because I care about results.

Compounds: GHK-Cu, DMSO
MMorph (@doctormorphh)view on X ↗
GHK-Cu is actually pretty neuroprotective. By donating copper ions to the electron transport chain it can enhance and heal complex IV in the METC, where most energy production happens.
If using GHK-Cu for skin/hair → apply topically (local). For general health benefits → subcutaneous.
[reply] DMSO is great to enhance topical absorption.

Compounds: GHK-Cu, DMSO