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Estradiol

Category: hormones

Information Sheet

What It Is

Estradiol is the primary oestrogen; mentioned as a topical cream with reported skin benefits in GHK-Cu skincare discussions.

Mechanism & Notes

  • Topical oestrogen supports skin collagen, thickness and hydration
  • Anecdotally combined with copper-peptide skincare regimens

Mentions

Rr/SkincareAddiction (Reddit thread)view on X ↗
Has anyone tried GHK-Cu? Thread consensus: injectable (subq) works far better than oral.
Doses ~0.5-3 mg/day or every other day; common effective dose ~1.75-2 mg/day. 35mg vial reconstituted in ~2.5ml bac water.
Positives: smoother glowing skin, fewer fine lines, 'glass skin' at ~1mg EOD. Negatives at high/prolonged dose: 'copper uglies' - sagging, dullness, breakouts, jowls (skin cycled too fast).
Cycle 30 on / 30 off (max 60/30). Lower dose for women. Often mixed with BPC-157 to reduce sting; supplement zinc (GHK-Cu uses zinc). One user noted estradiol cream gave good skin results.

Compounds: GHK-Cu, BPC-157, zinc, estradiol