GHK-Cu
Category: peptides
Mentions
Every supplement I have utilised to heal my gut to date:
- S. Boulardii
- Black seed oil
- Meriva Curcumin
- Lactoferrin
- Boswellia
- Quercetin
- Coconut oil
- Bismuth
- BPC157
- GHKcu
- Larazotide
- Butyrate
- Zinc L carnosine
- Spore based probiotics
- Beta caryphollene
- Lysozyme
- TUDCA
- Taurine
- Glycine
- Gelatine
- Magnesium
[Image shows lactoferrin powder bag, glycine powder bag, and other supplements]
7:12 PM · Jun 9, 2026 · 41.5K Views
Compounds: S. Boulardii, black seed oil, curcumin (Meriva), lactoferrin, boswellia, quercetin, coconut oil, bismuth, BPC-157, GHK-Cu, larazotide, butyrate, zinc L-carnosine, beta-caryophyllene, lysozyme, TUDCA, taurine, glycine, gelatine, magnesium
- S. Boulardii
- Black seed oil
- Meriva Curcumin
- Lactoferrin
- Boswellia
- Quercetin
- Coconut oil
- Bismuth
- BPC157
- GHKcu
- Larazotide
- Butyrate
- Zinc L carnosine
- Spore based probiotics
- Beta caryphollene
- Lysozyme
- TUDCA
- Taurine
- Glycine
- Gelatine
- Magnesium
[Image shows lactoferrin powder bag, glycine powder bag, and other supplements]
7:12 PM · Jun 9, 2026 · 41.5K Views
Compounds: S. Boulardii, black seed oil, curcumin (Meriva), lactoferrin, boswellia, quercetin, coconut oil, bismuth, BPC-157, GHK-Cu, larazotide, butyrate, zinc L-carnosine, beta-caryophyllene, lysozyme, TUDCA, taurine, glycine, gelatine, magnesium
When treating the gut, start with THIS check list:
1. Have you address inflammation (diet and life changes first, then metabolic or weight issues, and if need support meriva curcumin + boswellia, or even peptides like KPV)
2. Have you address digestion
- stomach acid via sufficient zinc, swedish bitters or arugula
- bile support via taurine, glycine, folate, B2, choline and b12
- iberogast/magnesium citrate if constipated
- digestive enzymes if low on test, have thyroid issues, or can't digest fats + starch
- trialled removing FODMAPs: starch, or other trigger foods – may need an elimination diet
3. Are you supporting any immune issue?
- may need to inhibit mast cell degranulation (boswellia, PEA, black seed oil, passionflower)
- support break down of histamine (via methylation nutrients, vitamin C, copper, DAO)
- elimination diet sometimes
4. Does your motility need support?
- if constipation (kiwi, iberagast, mg citrate, PHGG)
- if diarrhea (PHGG, fibre/starch in food as can tolerate)
5. Do you need to oxidative stress
- fruits and pomegranate juice as tolerated
- NAC with selenium and molybdenum
- black seed oil
6. Ensure you support the gut lining
- bone broth, collagen, glycine, gelatin
- zinc l carnosine
- s boulardii
- glutamine,
- peptides like BPC-157, larazotide, GHK or TBC500
- foods like okra and resistant starch as tolerated
7. Other factors
- sleep
- moderate exercise
- 10% calorie deficit but nutrient excess
- proper light environment practices and sufficient sunlight
- check cronometer for nutrients you're hitting, supplement what you aren't
- walk lots
- meditate or pray
This is a spring board to then work into your microbial/biofilm issues [truncated]
Compounds: curcumin (Meriva), boswellia, KPV peptide, zinc, taurine, glycine, folate, choline, magnesium citrate, PEA (palmitoylethanolamide), black seed oil, NAC, selenium, molybdenum, collagen, gelatin, zinc L-carnosine, S. boulardii, glutamine, BPC-157, larazotide, GHK, TBC500, vitamin C, copper, DAO
1. Have you address inflammation (diet and life changes first, then metabolic or weight issues, and if need support meriva curcumin + boswellia, or even peptides like KPV)
2. Have you address digestion
- stomach acid via sufficient zinc, swedish bitters or arugula
- bile support via taurine, glycine, folate, B2, choline and b12
- iberogast/magnesium citrate if constipated
- digestive enzymes if low on test, have thyroid issues, or can't digest fats + starch
- trialled removing FODMAPs: starch, or other trigger foods – may need an elimination diet
3. Are you supporting any immune issue?
- may need to inhibit mast cell degranulation (boswellia, PEA, black seed oil, passionflower)
- support break down of histamine (via methylation nutrients, vitamin C, copper, DAO)
- elimination diet sometimes
4. Does your motility need support?
- if constipation (kiwi, iberagast, mg citrate, PHGG)
- if diarrhea (PHGG, fibre/starch in food as can tolerate)
5. Do you need to oxidative stress
- fruits and pomegranate juice as tolerated
- NAC with selenium and molybdenum
- black seed oil
6. Ensure you support the gut lining
- bone broth, collagen, glycine, gelatin
- zinc l carnosine
- s boulardii
- glutamine,
- peptides like BPC-157, larazotide, GHK or TBC500
- foods like okra and resistant starch as tolerated
7. Other factors
- sleep
- moderate exercise
- 10% calorie deficit but nutrient excess
- proper light environment practices and sufficient sunlight
- check cronometer for nutrients you're hitting, supplement what you aren't
- walk lots
- meditate or pray
This is a spring board to then work into your microbial/biofilm issues [truncated]
Compounds: curcumin (Meriva), boswellia, KPV peptide, zinc, taurine, glycine, folate, choline, magnesium citrate, PEA (palmitoylethanolamide), black seed oil, NAC, selenium, molybdenum, collagen, gelatin, zinc L-carnosine, S. boulardii, glutamine, BPC-157, larazotide, GHK, TBC500, vitamin C, copper, DAO
Every supplement I have utilised to heal my gut to date:
- S. Boulardii
- Black seed oil
- Meriva Curcumin
- Lactoferrin
- Boswellia
- Quercetin
- Coconut oil
- Bismuth
- BPC157
- GHKcu
- Larazotide
- Butyrate
- Zinc L carnosine
- Spore based probiotics
- Beta caryphollene
- Lysozyme
- TUDCA
- Taurine
- Glycine
- Gelatine
- Magnesium
[Image shows supplement packaging for Lactoferrin and GLYCINE 100g]
7:12 PM · Jun 9, 2026 · 41.5K Views
Compounds: S. Boulardii, black seed oil, curcumin (Meriva), lactoferrin, boswellia, quercetin, coconut oil, bismuth, BPC-157, GHK-Cu, larazotide, butyrate, zinc L-carnosine, beta-caryophyllene, lysozyme, TUDCA, taurine, glycine, gelatine, magnesium
- S. Boulardii
- Black seed oil
- Meriva Curcumin
- Lactoferrin
- Boswellia
- Quercetin
- Coconut oil
- Bismuth
- BPC157
- GHKcu
- Larazotide
- Butyrate
- Zinc L carnosine
- Spore based probiotics
- Beta caryphollene
- Lysozyme
- TUDCA
- Taurine
- Glycine
- Gelatine
- Magnesium
[Image shows supplement packaging for Lactoferrin and GLYCINE 100g]
7:12 PM · Jun 9, 2026 · 41.5K Views
Compounds: S. Boulardii, black seed oil, curcumin (Meriva), lactoferrin, boswellia, quercetin, coconut oil, bismuth, BPC-157, GHK-Cu, larazotide, butyrate, zinc L-carnosine, beta-caryophyllene, lysozyme, TUDCA, taurine, glycine, gelatine, magnesium
your $120 peptide serum is probably 0.01% actual copper peptide. here's how to make a real 1% for a fraction of the price:
→ 100mg GHK-Cu vial (pharmaceutical grade)
→ 2ml bacteriostatic water - dissolve slowly
→ transfer to amber glass dropper bottle
→ add 8ml hyaluronic acid serum (The Ordinary HA 2% + B5)
→ total: 10ml at true 1% concentration. apply daily, store in fridge.
the compound itself is insane: GHK-Cu controls 4,000+ genes (32% of the genome). 200 ng/mL in your blood at 20, 80 ng/mL by 60.
clinical data: skin thickness up in 8 weeks; antioxidant defense up 58%; hair follicle growth in 6 DAYS (faster than minoxidil); 52-72 extra hairs in 6 months.
source matters more than the recipe - I use Good Science Bio (USA made).
Compounds: GHK-Cu, hyaluronic acid, minoxidil
→ 100mg GHK-Cu vial (pharmaceutical grade)
→ 2ml bacteriostatic water - dissolve slowly
→ transfer to amber glass dropper bottle
→ add 8ml hyaluronic acid serum (The Ordinary HA 2% + B5)
→ total: 10ml at true 1% concentration. apply daily, store in fridge.
the compound itself is insane: GHK-Cu controls 4,000+ genes (32% of the genome). 200 ng/mL in your blood at 20, 80 ng/mL by 60.
clinical data: skin thickness up in 8 weeks; antioxidant defense up 58%; hair follicle growth in 6 DAYS (faster than minoxidil); 52-72 extra hairs in 6 months.
source matters more than the recipe - I use Good Science Bio (USA made).
Compounds: GHK-Cu, hyaluronic acid, minoxidil
Please don't do this. Reconstituted GHK-Cu in bac water has awful skin penetration, because it's highly polar, hydrophilic, and copper-bound - passive diffusion through intact skin is pretty much impossible.
Cosmetic GHK-Cu products are formulated with penetration enhancers and optimized vehicles for a reason. Repeatedly wiping benzyl alcohol on your face isn't a skincare hack - at least use sterile water.
[reply] DMSO will help, but it's a sledgehammer - a very aggressive penetration enhancer.
I buy my GHK-Cu serum from @sevo_skincare because I care about results.
Compounds: GHK-Cu, DMSO
Cosmetic GHK-Cu products are formulated with penetration enhancers and optimized vehicles for a reason. Repeatedly wiping benzyl alcohol on your face isn't a skincare hack - at least use sterile water.
[reply] DMSO will help, but it's a sledgehammer - a very aggressive penetration enhancer.
I buy my GHK-Cu serum from @sevo_skincare because I care about results.
Compounds: GHK-Cu, DMSO
first of all you must be a fool to pay the price of a sterilized vial while you can get a lot more if you buy raw powder.
second you can get a cream base very cheap (e.g. CHEMCO aqueous cream base 400gr) to make a topical GHK-Cu yourself.
Compounds: GHK-Cu
second you can get a cream base very cheap (e.g. CHEMCO aqueous cream base 400gr) to make a topical GHK-Cu yourself.
Compounds: GHK-Cu
The benefits of GHK-Cu are insane:
- In human trials, it increased collagen 51% in 3 months
- Outperformed vitamin C AND retinoic acid for collagen
- Beat Matrixyl 3000 (a leading anti-aging peptide) by 31.6% wrinkle reduction
- Resets 31% of the human genome
- Triggers cancer cells' natural self-destruct mechanism
Yet most people only see it as a 'skincare ingredient.' Injectable GHK-Cu available (50 mg).
Compounds: GHK-Cu, vitamin C, retinoic acid, Matrixyl 3000
- In human trials, it increased collagen 51% in 3 months
- Outperformed vitamin C AND retinoic acid for collagen
- Beat Matrixyl 3000 (a leading anti-aging peptide) by 31.6% wrinkle reduction
- Resets 31% of the human genome
- Triggers cancer cells' natural self-destruct mechanism
Yet most people only see it as a 'skincare ingredient.' Injectable GHK-Cu available (50 mg).
Compounds: GHK-Cu, vitamin C, retinoic acid, Matrixyl 3000
Collagen decides the texture/appearance of your skin and hair. Peptides like GHK-Cu improve collagen synthesis.
But to ACTUALLY improve collagen synthesis you need its building blocks: Glycine, Glutamine, Alanine and (hydroxy)Proline.
The average 70kg human is around 10 grams deficient in Glycine, the main component of collagen.
Where to find these building blocks: collagen, gelatin, bone broth. Eat ~30g of gelatin daily.
Compounds: collagen, gelatin, glycine, glutamine, alanine, hydroxyproline, GHK-Cu
But to ACTUALLY improve collagen synthesis you need its building blocks: Glycine, Glutamine, Alanine and (hydroxy)Proline.
The average 70kg human is around 10 grams deficient in Glycine, the main component of collagen.
Where to find these building blocks: collagen, gelatin, bone broth. Eat ~30g of gelatin daily.
Compounds: collagen, gelatin, glycine, glutamine, alanine, hydroxyproline, GHK-Cu
KLOW rebuilds tendons, seals ulcers, regrows skin, and shuts down inflammation - at the same time.
KLOW is BPC-157, TB-500, GHK-Cu, and KPV. Four peptides. Four mechanisms.
• BPC-157 rebuilds gut and tendon tissue.
• TB-500 mobilizes repair cells across the body.
• GHK-Cu activates 4,000+ healing genes.
• KPV shuts down inflammation at the source.
Together they have welded tendon to bone, sealed bleeding ulcers, closed diabetic wounds, faded scars, protected the brain, sealed corneal punctures.
Refs: KPV - Dalmasso 2008 (PMID 18061177); BPC-157 Achilles tendon-to-bone (PMID 16583442).
Compounds: KLOW (GHK-Cu + BPC-157 + TB-500 + KPV)
KLOW is BPC-157, TB-500, GHK-Cu, and KPV. Four peptides. Four mechanisms.
• BPC-157 rebuilds gut and tendon tissue.
• TB-500 mobilizes repair cells across the body.
• GHK-Cu activates 4,000+ healing genes.
• KPV shuts down inflammation at the source.
Together they have welded tendon to bone, sealed bleeding ulcers, closed diabetic wounds, faded scars, protected the brain, sealed corneal punctures.
Refs: KPV - Dalmasso 2008 (PMID 18061177); BPC-157 Achilles tendon-to-bone (PMID 16583442).
Compounds: KLOW (GHK-Cu + BPC-157 + TB-500 + KPV)
GHK-Cu is actually pretty neuroprotective. By donating copper ions to the electron transport chain it can enhance and heal complex IV in the METC, where most energy production happens.
If using GHK-Cu for skin/hair → apply topically (local). For general health benefits → subcutaneous.
[reply] DMSO is great to enhance topical absorption.
Compounds: GHK-Cu, DMSO
If using GHK-Cu for skin/hair → apply topically (local). For general health benefits → subcutaneous.
[reply] DMSO is great to enhance topical absorption.
Compounds: GHK-Cu, DMSO
Copper peptide (GHK-Cu) is a tiny molecule the body makes, central to skin and follicle repair. Levels drop ~60% from your twenties to sixties.
When GHK-Cu reaches the follicle it: activates Wnt/β-catenin (master growth switch), upregulates VEGF (blood supply), rebuilds the collagen scaffold - without altering androgens.
A 2024 paper (Liu et al., Bioactive Materials) showed GHK-Cu works only when wrapped in a delivery system increasing penetration ~3x.
[reply] topical copper peptides appear to work even better than injectable for hair (combined with BPC-157).
Compounds: GHK-Cu, BPC-157
When GHK-Cu reaches the follicle it: activates Wnt/β-catenin (master growth switch), upregulates VEGF (blood supply), rebuilds the collagen scaffold - without altering androgens.
A 2024 paper (Liu et al., Bioactive Materials) showed GHK-Cu works only when wrapped in a delivery system increasing penetration ~3x.
[reply] topical copper peptides appear to work even better than injectable for hair (combined with BPC-157).
Compounds: GHK-Cu, BPC-157
LOOKSMAXX SKIN THROUGH HEALTH:
- daily 10-15mL black seed oil in the morning
- weekly 200g of calf's liver
- weekly 1-2 dozen oysters
- sunlight / red light therapy
- tallow balm on face (w/ GHK-Cu maybe)
- gelatin + taurine in coffee
- topical royal jelly
- walking daily
- Ray Peat carrot salad + well-cooked white button mushrooms daily
Compounds: black seed oil, red light therapy, tallow, GHK-Cu, gelatin, taurine, royal jelly
- daily 10-15mL black seed oil in the morning
- weekly 200g of calf's liver
- weekly 1-2 dozen oysters
- sunlight / red light therapy
- tallow balm on face (w/ GHK-Cu maybe)
- gelatin + taurine in coffee
- topical royal jelly
- walking daily
- Ray Peat carrot salad + well-cooked white button mushrooms daily
Compounds: black seed oil, red light therapy, tallow, GHK-Cu, gelatin, taurine, royal jelly
GHK-Cu literally ACTIVATED 4,000+ healing genes in aged human skin cells. It's a copper peptide your body makes naturally - at 20 your blood is full of it, by 60 you have a third as much.
It triggers fibroblasts to multiply, rebuilds collagen, regenerates damaged skin, and reverses photoaging in biopsied tissue.
In studies it also regrew hair on bald scalps, supported nerve regeneration, accelerated bone repair, restored aged lung cells, restored cognition in old mice, extended lifespan in animal studies.
Ref: PMC8789089 (cited as Pickart 2022; the PMC8789089 article is actually Dou et al. 2020, 'The potential of GHK as an anti-aging peptide').
Compounds: GHK-Cu (see paper PMC8789089)
It triggers fibroblasts to multiply, rebuilds collagen, regenerates damaged skin, and reverses photoaging in biopsied tissue.
In studies it also regrew hair on bald scalps, supported nerve regeneration, accelerated bone repair, restored aged lung cells, restored cognition in old mice, extended lifespan in animal studies.
Ref: PMC8789089 (cited as Pickart 2022; the PMC8789089 article is actually Dou et al. 2020, 'The potential of GHK as an anti-aging peptide').
Compounds: GHK-Cu (see paper PMC8789089)
GHK is simply unmatched for skin quality and hair growth. GHK-Cu is a natural peptide found in blood and skin, released in response to injury/inflammation.
Skin: increases collagen + elastin synthesis, stimulates repair signalling, migrates stem cells. Hair: stimulates new blood vessel creation, increases hair diameter, enlarges follicles.
Apply just enough to cover face/scalp once (better twice) daily; combine with dermarolling/microneedling. Topical works ~as well as injection WHEN formulated in liposomes (lipid nanoparticles).
Refs: PMID 29986520, 26236730, 28370978, 27489425.
Compounds: GHK-Cu (refs PMID 29986520, 26236730, 28370978, 27489425)
Skin: increases collagen + elastin synthesis, stimulates repair signalling, migrates stem cells. Hair: stimulates new blood vessel creation, increases hair diameter, enlarges follicles.
Apply just enough to cover face/scalp once (better twice) daily; combine with dermarolling/microneedling. Topical works ~as well as injection WHEN formulated in liposomes (lipid nanoparticles).
Refs: PMID 29986520, 26236730, 28370978, 27489425.
Compounds: GHK-Cu (refs PMID 29986520, 26236730, 28370978, 27489425)
GHK-Cu before and after. Used subcutaneous injections, 1 mg every night before bed (others go higher, but I kept it at 1mg to avoid excess copper accumulation). Effects after ~a month:
- hair stopped falling out, regrew in bald spots, fuzz on receding hairline
- gray hair on top darkened back to black/brown
- 'chicken skin' (keratosis pilaris) on triceps cleared
- roughly 5 years of hair regrowth within months.
Compounds: GHK-Cu
- hair stopped falling out, regrew in bald spots, fuzz on receding hairline
- gray hair on top darkened back to black/brown
- 'chicken skin' (keratosis pilaris) on triceps cleared
- roughly 5 years of hair regrowth within months.
Compounds: GHK-Cu
Has anyone tried GHK-Cu? Thread consensus: injectable (subq) works far better than oral.
Doses ~0.5-3 mg/day or every other day; common effective dose ~1.75-2 mg/day. 35mg vial reconstituted in ~2.5ml bac water.
Positives: smoother glowing skin, fewer fine lines, 'glass skin' at ~1mg EOD. Negatives at high/prolonged dose: 'copper uglies' - sagging, dullness, breakouts, jowls (skin cycled too fast).
Cycle 30 on / 30 off (max 60/30). Lower dose for women. Often mixed with BPC-157 to reduce sting; supplement zinc (GHK-Cu uses zinc). One user noted estradiol cream gave good skin results.
Compounds: GHK-Cu, BPC-157, zinc, estradiol
Doses ~0.5-3 mg/day or every other day; common effective dose ~1.75-2 mg/day. 35mg vial reconstituted in ~2.5ml bac water.
Positives: smoother glowing skin, fewer fine lines, 'glass skin' at ~1mg EOD. Negatives at high/prolonged dose: 'copper uglies' - sagging, dullness, breakouts, jowls (skin cycled too fast).
Cycle 30 on / 30 off (max 60/30). Lower dose for women. Often mixed with BPC-157 to reduce sting; supplement zinc (GHK-Cu uses zinc). One user noted estradiol cream gave good skin results.
Compounds: GHK-Cu, BPC-157, zinc, estradiol
GHK is endogenous to human serum and declines ~2.5-fold with age (200→80 ng/ml). GHK-Cu raises bFGF/VEGF, promotes angiogenesis and wound healing (incl. liposomal delivery), is antioxidant/anti-inflammatory (cuts ROS ~50%, suppresses TNF-α/IL-6), and improves spatial learning in aged mice within ~3 weeks. (PMC8789089; this article is Dou et al. 2020, not Pickart 2022.)
Compounds: ghk-cu
Compounds: ghk-cu
GHK-Cu reference set: Pickart & Margolina 2018 (PMID 29986520, gene-level regenerative/protective actions); Pickart 2015 (PMID 26236730, modulates collagen/GAG synthesis + MMPs); Hyun 2017 (PMID 28370978, GHK-Cu liposomes speed scald healing via angiogenesis); 2016 ALA+GHK hair study (PMID 27489425, modest hair-count gain).
Compounds: ghk-cu
Compounds: ghk-cu