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Glycine

Category: amino_acids

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DDalton (Analyze & Optimize) (@Outdoctrination)Screenshot 2026-06-16 at 19.35.39.png.txt
Jun 10 tweet about glycine anti-seizure effect

Glycine has an anti-seizure effect in experiments.

Multiple animal studies show that adding glycine into the water improves the anticonvulsant properties of several drugs.

This is likely due to glycine's ability to bind glycine receptors in the brain — which have inhibitory effects on brain activity.

[Image shows research paper: "Glycine Potentiation of Anticonvulsant Drugs in Pentylenetetrazol Seizures in Rats" — Steven L. Peterson, Department of Medical Pharmacology and Toxicology, Texas A&M University, College Station, TX 77843]

Compounds: glycine
DDalton (Analyze & Optimize) (@Outdoctrination)view on X ↗
Glycine + NAC reverse nearly all signs of aging + metabolic disease in 2 weeks. [study]

The two synergize to improve glutathione production, for some incredible results:

◆ Glutathione synthesis rate ↑ -120%
◆ Total glutathione ↑ ~50%
◆ GSH/GSSG ratio ↑ ~125%
◆ Plasma reactive oxygen metabolites ↓ ~50%
◆ Plasma F2-isoprostanes (oxidative stress) ↓ ~35%

It also improved oxidative metabolism:
◆ Fasted NEFA oxidation ↑ ~50%
◆ Fed NEFA oxidation ↑ ~70%
◆ Fed carbohydrate oxidation ↑ ~20%
◆ Suppression of NEFA oxidation (fed vs fasted) ↑ ~135%
◆ Stimulation of carbohydrate oxidation (fed vs fasted) ↑ ~690%
◆ Insulin sensitivity index ↑ ~35%

AND body composition:
◆ Fat mass: 21.6 → 20.0 kg
◆ Fat-free mass: 60.1 → 61.0 kg
◆ Muscle strength (dominant arm): 35 → 37
◆ Muscle strength (nondominant arm): 31 → 34

They did do megadoses - 9g NAC + 7g glycine, but a lower daily maintenance dose would work as well.

[Graph showing glycine + NAC vs placebo results across oxidative stress and metabolic markers]

Compounds: glycine, NAC (N-acetylcysteine), glutathione, NEFA
MMetabolic Blueprint (@metabolic_print)view on X ↗
Nightly chocolate milk

- 10g colostrum
- 5g taurine
- 5g glycine
- 50g sugar

I'm really about that life

[Image shows a glass of chocolate milk being held in a kitchen]
10:48 PM · Mar 18, 2026 · 5,153 Views

[Reply from Metabolic Blueprint @metabolic_print - Mar 18: Don't care + sugarmaxxing + having chocolate milk
No cortisol to be found in me x.com/DionysianAgent...]
[Image shows muscular man with supplement bags]

Compounds: colostrum, taurine, glycine
SSam (@theholisticgut)view on X ↗
Every supplement I have utilised to heal my gut to date:

- S. Boulardii
- Black seed oil
- Meriva Curcumin
- Lactoferrin
- Boswellia
- Quercetin
- Coconut oil
- Bismuth
- BPC157
- GHKcu
- Larazotide
- Butyrate
- Zinc L carnosine
- Spore based probiotics
- Beta caryphollene
- Lysozyme
- TUDCA
- Taurine
- Glycine
- Gelatine
- Magnesium

[Image shows lactoferrin powder bag, glycine powder bag, and other supplements]
7:12 PM · Jun 9, 2026 · 41.5K Views

Compounds: S. Boulardii, black seed oil, curcumin (Meriva), lactoferrin, boswellia, quercetin, coconut oil, bismuth, BPC-157, GHK-Cu, larazotide, butyrate, zinc L-carnosine, beta-caryophyllene, lysozyme, TUDCA, taurine, glycine, gelatine, magnesium
RRoss (@GutOptimized)view on X ↗
If you're experiencing pain and bloating in your gut every time you eat, this is a supplement stack you can try:

1. Curcumin mervia (1000mg twice daily)
2. NAC (1000mg twice daily)
3. Glycine (5-10g daily)
4. Black seed oil (60 mins post meal)
5. S Boulardii (1 tab 60 mins post meal)

Food wise, try either
1. Low starch, or
2. Low FODMAP

To aid other potential issues with digestion, try:
1. ACV (diluted) before food
2. Try betaine HCL with food (start low dose)
3. Try one 250-500mg TUDCA with food
4. Try digestive enzymes with food

And take out any bigger triggers like gluten.

If the above isn't enough to improve symptoms, you may need to look much deeper.

Have you tried something like this? Did it help?

10:37 PM · Nov 26, 2025 · 213K Views

Compounds: curcumin (Meriva), NAC, glycine, black seed oil, S. Boulardii, ACV (apple cider vinegar), betaine HCL, TUDCA, digestive enzymes
GGunnar (@FarvingCo)Screenshot 2026-06-16 at 20.12.27.png.txt
https://x.com/FarvingCo/status/1912858935250068213 (approx.)

These are the best supplements:

- Gelatin / glycine
- Glutamine
- Lactoferrin
- Mastic gum
- Sodium Butyrate
- Zinc Carnosine

If you want to experiment with peptides, BPC-157 is insane for gut health

Cut out all irritating foods, eat only nutrient dense whole foods:

- Dairy
- Meat
- Gelatin/bone broth
- Eggs
- Organs (liver, heart)
- Oysters
- Shilajit
- Bee pollen
- Dark chocolate
- Royal jelly
- Colostrum powder

Hope this helps.

2:23 PM · Apr 11, 2025 · 204 Views

Compounds: gelatin, glycine, glutamine, lactoferrin, mastic gum, sodium butyrate, zinc carnosine, BPC-157, shilajit, bee pollen, royal jelly, colostrum
HHans Amato (@HansAmato)view on X ↗
Men in their late 30s are looking 40 and nobody is telling them why

Puffy face. Grey skin. Eye bags at noon. People guessing their age wrong by a decade.

It's not genetics. It's inflammation aging the body from the Inside out

The puffiness under the eyes is fluid retention from a gut that's been sending endotoxins into the lymphatics for years.

The dull skin is a liver so backed up with endotoxin that it can't clear the waste that shows up on the face

Aging happens when cells can't repair faster than they're being damaged. Inflammation accelerates that damage. Every single day.

The guys who "age well" aren't genetic freaks.

They fix the gut. When gut inflammation dies, hormones return to where they should be. Their body can spend resources on repair instead of firefighting.

The $500 billion skincare industry is topical products trying to fix a problem that starts in the gut. Moisturizer doesn't fix internal inflammation

I wasted 5 years younger with puffiness. Face gone. Skin dull. Dark circles healed. Skin cleaned. People asked if I'd lost weight.

Wasn't exercise. Just stopped being inflamed.

What actually works:
- Fix the gut. Endotoxin from a leaky gut drives the systemic inflammation that ages every tissue in the body. Bone broth, L-glutamine, L-carnosine. Stop caffeine on an empty stomach
- Cut seed oils. They oxidize in the cell membranes and accelerate aging at the cellular level. Cook in butter, ghee, tallow.
- Eat enough. Undereating suppresses thyroid. Low thyroid = puffy face, dull skin, thinning hair, fluid retention. Every "anti-aging" influencer is fasting and wondering why they look older
- Liver support. The liver cleans the waste that shows up on your skin. Glycine, enough protein to fuel detox pathways. Overwhelm nothing.
- Magnesium and zinc. Both required for skin cell turnover and collagen synthesis. Both depleted by stress
- Sleep 7-8 hours. Growth hormone peaks during deep sleep. Growth hormone drives tissue repair. No deep sleep = no repair = faster aging
- The face is a dashboard for internal health. Every puff, every circle, every premature line is the body showing what's wrong underneath.

Spending $200/month on serums while eating seed oils and sleeping 5 hours is treating the dashboard light without opening the hood

DM me "REPORT" for the custom health report

Compounds: L-glutamine, L-carnosine, glycine, magnesium, zinc
GGutOptimized (@GutOptimized)view on X ↗
When treating the gut, start with THIS check list:

1. Have you address inflammation (diet and life changes first, then metabolic or weight issues, and if need support meriva curcumin + boswellia, or even peptides like KPV)

2. Have you address digestion
- stomach acid via sufficient zinc, swedish bitters or arugula
- bile support via taurine, glycine, folate, B2, choline and b12
- iberogast/magnesium citrate if constipated
- digestive enzymes if low on test, have thyroid issues, or can't digest fats + starch
- trialled removing FODMAPs: starch, or other trigger foods – may need an elimination diet

3. Are you supporting any immune issue?
- may need to inhibit mast cell degranulation (boswellia, PEA, black seed oil, passionflower)
- support break down of histamine (via methylation nutrients, vitamin C, copper, DAO)
- elimination diet sometimes

4. Does your motility need support?
- if constipation (kiwi, iberagast, mg citrate, PHGG)
- if diarrhea (PHGG, fibre/starch in food as can tolerate)

5. Do you need to oxidative stress
- fruits and pomegranate juice as tolerated
- NAC with selenium and molybdenum
- black seed oil

6. Ensure you support the gut lining
- bone broth, collagen, glycine, gelatin
- zinc l carnosine
- s boulardii
- glutamine,
- peptides like BPC-157, larazotide, GHK or TBC500
- foods like okra and resistant starch as tolerated

7. Other factors
- sleep
- moderate exercise
- 10% calorie deficit but nutrient excess
- proper light environment practices and sufficient sunlight
- check cronometer for nutrients you're hitting, supplement what you aren't
- walk lots
- meditate or pray

This is a spring board to then work into your microbial/biofilm issues [truncated]

Compounds: curcumin (Meriva), boswellia, KPV peptide, zinc, taurine, glycine, folate, choline, magnesium citrate, PEA (palmitoylethanolamide), black seed oil, NAC, selenium, molybdenum, collagen, gelatin, zinc L-carnosine, S. boulardii, glutamine, BPC-157, larazotide, GHK, TBC500, vitamin C, copper, DAO
SSam (@theholisticgut)view on X ↗
Every supplement I have utilised to heal my gut to date:

- S. Boulardii
- Black seed oil
- Meriva Curcumin
- Lactoferrin
- Boswellia
- Quercetin
- Coconut oil
- Bismuth
- BPC157
- GHKcu
- Larazotide
- Butyrate
- Zinc L carnosine
- Spore based probiotics
- Beta caryphollene
- Lysozyme
- TUDCA
- Taurine
- Glycine
- Gelatine
- Magnesium

[Image shows supplement packaging for Lactoferrin and GLYCINE 100g]
7:12 PM · Jun 9, 2026 · 41.5K Views

Compounds: S. Boulardii, black seed oil, curcumin (Meriva), lactoferrin, boswellia, quercetin, coconut oil, bismuth, BPC-157, GHK-Cu, larazotide, butyrate, zinc L-carnosine, beta-caryophyllene, lysozyme, TUDCA, taurine, glycine, gelatine, magnesium
Aaestheticprimal (@aestheticprimal)view on X ↗
Collagen decides the texture/appearance of your skin and hair. Peptides like GHK-Cu improve collagen synthesis.
But to ACTUALLY improve collagen synthesis you need its building blocks: Glycine, Glutamine, Alanine and (hydroxy)Proline.
The average 70kg human is around 10 grams deficient in Glycine, the main component of collagen.
Where to find these building blocks: collagen, gelatin, bone broth. Eat ~30g of gelatin daily.

Compounds: collagen, gelatin, glycine, glutamine, alanine, hydroxyproline, GHK-Cu