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ISRIB

Category: nootropics

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MMorph (@doctormorphh)view on X ↗
If you want autistic cognition without tweaking like you took some 99% Walter White special the stack would look something like:

Intranasal insulin 20IU
For removing distractions, improving memory formation and neuroprotection.

Dihexa 5mg
Potentiates memory formation even more, protects dopamine producing neurons and reduces neuro inflammation.

Guanfacine 1mg
Guanfacine is the opposite of a stimulant. It reduces firing in the prefrontal cortex which strengthens whatever firing happens making the connection stronger. Your brain is less noisy --> better cognition. Good for sleep and growth hormone as well. More BDNF. Restores dopaminergic signaling.

CDP-choline 300mg
Mitochondrial support, increases acetylcholine and citidine, increases dopamine and dopamine receptor density. Easy to get.

ISRIB 20mg
Makes sure anything related to stress does not negatively impact cognition without stimulating. Makes sure eLF2B gets activated which ensures memory formation and focus can stay dialed in.

Dialed in for the rest of the night.

Compounds: intranasal insulin, Dihexa, guanfacine, CDP-choline (citicoline), ISRIB
MMorph (@doctormorphh)Screenshot 2026-06-17 at 21.47.40.png.txt
perfect mental enhancement stack for if you are sleep deprived or have a test in 30 minutes: ISRIB, cerebrolysin, intranasal insulin, nebivolol, tak-653, magnesium-l-threonate