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Melatonin

Category: sleep

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AAndra (@BioavailableNd)view on X ↗
Want a healthy gut barrier integrity? One needs to protect & regulate the gut sealing protein: Claudin-3.
Low Claudin-3 = compromised barrier = higher risk of systemic inflammation, autoimmunity, and neurological diseases. Compounds that preserve Claudin-3:
- Vitamin D
- Zinc L-Carnosine
- Lactoferrin / Colostrum
- L-Glutamine
- Butyrate / Tributyrin
- Gelatin / Bone Broth
- Quercetin
- Curcumin
- Apigenin
- EGCG

12:58 AM · Apr 23, 2025 · 33.8K Views

[Reply from Andra @BioavailableNd - Apr 23, 2025: It could be as simple as daily sunlight, a few glasses of raw milk for lactoferrin, bone broth with onions peels for quercetin and gelatine, a few cups of green tea or chamomile tea a week and cooking with lots of culinary herbs and spices. Or supplements like Gut Health Combo by @objectivenutri if needed for acute issues.]

[Reply from DOMO @BOOMHealth - Apr 23, 2025: Excellent list, Andra. Just to add a quantum biology layer: Claudin-3 isn't only influenced by nutrients, it's regulated by mitochondrial redox rhythm, circadian gene expression, and photonic signaling.
- Melatonin (synthesized locally in GI tract) preserves Claudin-3 via...]

Compounds: vitamin D, zinc L-carnosine, lactoferrin, colostrum, L-glutamine, butyrate, tributyrin, gelatin, quercetin, curcumin, apigenin, EGCG, melatonin