Meldonium
Category: cardiovascular
Mentions
bromantane is not what you think it is and is used for the wrong reasons at wrong doses
most people use it for its dopaminergic effects but are taking 10 times more a dose than what the studies on its 'dopaminergic' effects showed
some things its good for:
acute stress
anxiolysis
motor function
fatigue
physical performance
yes it can increase dopamine content in several places of the brain but those placed arent nearly as crucial for ACTUAL cognition as other places like the pfc:
NAc
hypothalamus
hippocampus
VTA
striatum
increasing dopamine here is not a wide spread cognition upgrade or whatever it seems like. It can help with motivation, stress, motor function and reward signaling.
not to mention the increase was seen at 50 mg/kg in rodents and when using the HED calculations it would come out at 567 mg dose, a day.
the lowest dose used showing any sign of dopaminergic effects sits around 137mg for a human.
I would use this more as a compound like meldonium and with that I mean taking it to enhance physical activity, especially one that needs a bit of extra motivation and I would dose it at 150-300mg and -500mg when seeking to increase baseline dopamine and motivation.
though at that point you are better off with other compounds.
the bottom line here is simple;
you are using a compound for motivation based on data that has shown pretty non-impressive effects at doses 10x higher than the doses you are taking.
bromantane is more anxiolytic, anti-inflammation and pro motor function than a dopaminergic compound.
Compounds: bromantane, meldonium
most people use it for its dopaminergic effects but are taking 10 times more a dose than what the studies on its 'dopaminergic' effects showed
some things its good for:
acute stress
anxiolysis
motor function
fatigue
physical performance
yes it can increase dopamine content in several places of the brain but those placed arent nearly as crucial for ACTUAL cognition as other places like the pfc:
NAc
hypothalamus
hippocampus
VTA
striatum
increasing dopamine here is not a wide spread cognition upgrade or whatever it seems like. It can help with motivation, stress, motor function and reward signaling.
not to mention the increase was seen at 50 mg/kg in rodents and when using the HED calculations it would come out at 567 mg dose, a day.
the lowest dose used showing any sign of dopaminergic effects sits around 137mg for a human.
I would use this more as a compound like meldonium and with that I mean taking it to enhance physical activity, especially one that needs a bit of extra motivation and I would dose it at 150-300mg and -500mg when seeking to increase baseline dopamine and motivation.
though at that point you are better off with other compounds.
the bottom line here is simple;
you are using a compound for motivation based on data that has shown pretty non-impressive effects at doses 10x higher than the doses you are taking.
bromantane is more anxiolytic, anti-inflammation and pro motor function than a dopaminergic compound.
Compounds: bromantane, meldonium
cortxin + 9-me-bc = dopaminergic system restoration
PQQ + ubiquinol = elite preworkout
TTFD + methylated B-vitamins = ridiculous energy
dihexa + nicotine = elite writing & memory
[Reply from BasedBiohacker @BasedBiohacker - Jun 10: epitalon = amazing sleep
modafinil + bromantane = amazing focus
psilocybin + mexidol = amazing charisma
meldonium + tadalafil = amazing stamina
selank + fasopracetam = amazingly calm...]
[Image of a person walking on a glowing path at night in a field]
4:59 PM · Jun 10, 2026 · 15K Views
Compounds: cortxin, 9-ME-BC (9-methyl-beta-carboline), PQQ, ubiquinol, TTFD (thiamine tetrahydrofurfuryl disulfide), methylated B-vitamins, Dihexa, nicotine, epitalon, modafinil, bromantane, psilocybin, mexidol, meldonium, tadalafil, selank, fasopracetam
PQQ + ubiquinol = elite preworkout
TTFD + methylated B-vitamins = ridiculous energy
dihexa + nicotine = elite writing & memory
[Reply from BasedBiohacker @BasedBiohacker - Jun 10: epitalon = amazing sleep
modafinil + bromantane = amazing focus
psilocybin + mexidol = amazing charisma
meldonium + tadalafil = amazing stamina
selank + fasopracetam = amazingly calm...]
[Image of a person walking on a glowing path at night in a field]
4:59 PM · Jun 10, 2026 · 15K Views
Compounds: cortxin, 9-ME-BC (9-methyl-beta-carboline), PQQ, ubiquinol, TTFD (thiamine tetrahydrofurfuryl disulfide), methylated B-vitamins, Dihexa, nicotine, epitalon, modafinil, bromantane, psilocybin, mexidol, meldonium, tadalafil, selank, fasopracetam
the meldonium + tadalafil + bromantane + modafinil stack is STUPID GOOD for cognitive and performance enhancement:
→ tadalafil increases cerebral blood flow; more oxygen and nutrients reaching your brain
→ meldonium shifts neurons to use glucose more efficiently under that increased delivery
→ modafinil drives acute focus and wakefulness on top of the already optimized foundation
→ bromantane upregulates tyrosine hydroxylase so your dopamine production capacity actually builds instead of depleting
blood flow → neural efficiency → cognitive output → neurotransmitter sustainability
four different entry points all converging on a beautiful path of pure fucking output
and then you just munch on skittles and gummy bears as your carb source throughout the day as meldonium literally shifts your metabolism toward glucose utilization, also incredibly important to hydrate with electrolytes throughout the day as glucose metabolization uses up massive amounts of magnesium and potassium
you literally become a well-oiled pharmacological MACHINE running on fucking candy and all-ends optimization
add pinealon and epitalon for sleep and you might get the midas touch
not medical advice, and definitely start on low doses (can be heavy on the cardiovascular system for some) but this is the schedule i follow
- meldonium sublingual 500-1000 mg 6 weeks on, several months off (supplement l-carnitine when you go off)
- modafinil 100-200 mg
- bromantane sublingual 50 mg (daily)
- tadalafil 5 mg daily
again, not medical advice... this is high level shit
all sources and info here: basedbiohacker.any.org/cognitive-enha...
us sources linked below (comment if you know domestic us meldonium source)
Compounds: meldonium, tadalafil, bromantane, modafinil, pinealon, epitalon, l-carnitine, magnesium, potassium
→ tadalafil increases cerebral blood flow; more oxygen and nutrients reaching your brain
→ meldonium shifts neurons to use glucose more efficiently under that increased delivery
→ modafinil drives acute focus and wakefulness on top of the already optimized foundation
→ bromantane upregulates tyrosine hydroxylase so your dopamine production capacity actually builds instead of depleting
blood flow → neural efficiency → cognitive output → neurotransmitter sustainability
four different entry points all converging on a beautiful path of pure fucking output
and then you just munch on skittles and gummy bears as your carb source throughout the day as meldonium literally shifts your metabolism toward glucose utilization, also incredibly important to hydrate with electrolytes throughout the day as glucose metabolization uses up massive amounts of magnesium and potassium
you literally become a well-oiled pharmacological MACHINE running on fucking candy and all-ends optimization
add pinealon and epitalon for sleep and you might get the midas touch
not medical advice, and definitely start on low doses (can be heavy on the cardiovascular system for some) but this is the schedule i follow
- meldonium sublingual 500-1000 mg 6 weeks on, several months off (supplement l-carnitine when you go off)
- modafinil 100-200 mg
- bromantane sublingual 50 mg (daily)
- tadalafil 5 mg daily
again, not medical advice... this is high level shit
all sources and info here: basedbiohacker.any.org/cognitive-enha...
us sources linked below (comment if you know domestic us meldonium source)
Compounds: meldonium, tadalafil, bromantane, modafinil, pinealon, epitalon, l-carnitine, magnesium, potassium
a few compounds that make natty boys look RETARDED
- bromantane
- epitalon
- meldonium
- pinealon
- royal jelly
- low dose tadalafil
[Image shows muscular bald older man]
[Attached quote from limitlesstack @limitlesstack - Feb 22: "I am a nootropic combination expert. you want executive function? you want neuroplasticity? you want to finish that 6-month project in one weekend? you want to lift mood and crush depression?..."]
5:27 PM · May 25, 2026 · 37.5K Views
Compounds: bromantane, epitalon, meldonium, pinealon, royal jelly, tadalafil
- bromantane
- epitalon
- meldonium
- pinealon
- royal jelly
- low dose tadalafil
[Image shows muscular bald older man]
[Attached quote from limitlesstack @limitlesstack - Feb 22: "I am a nootropic combination expert. you want executive function? you want neuroplasticity? you want to finish that 6-month project in one weekend? you want to lift mood and crush depression?..."]
5:27 PM · May 25, 2026 · 37.5K Views
Compounds: bromantane, epitalon, meldonium, pinealon, royal jelly, tadalafil
It's another way of saying: I eat döner kebabs and donuts every day, but I stack high doses of vitamin E, aspirin, niacinamide, meldonium, B1, T3, DNP to offset PUFA damage and keep lipid peroxidation in check.
[Quote from Metabolic Hell @MetabolicHell (Parody account) - Apr 12: "Fuck this peating shit I'm a Haiduter now"]
1:55 PM · Apr 12, 2026 · 23.5K Views
[Reply from Richard @PGCTs_R8 - Apr 12: "I take exemestane so I can drink more liquor"]
[Reply from Jamal Dinkoul @BerbarianWizard - Apr 12: Very few people get the reference]
Compounds: vitamin E, aspirin, niacinamide, meldonium, vitamin B1 (thiamine), T3 (triiodothyronine), DNP (2,4-dinitrophenol), PUFA
[Quote from Metabolic Hell @MetabolicHell (Parody account) - Apr 12: "Fuck this peating shit I'm a Haiduter now"]
1:55 PM · Apr 12, 2026 · 23.5K Views
[Reply from Richard @PGCTs_R8 - Apr 12: "I take exemestane so I can drink more liquor"]
[Reply from Jamal Dinkoul @BerbarianWizard - Apr 12: Very few people get the reference]
Compounds: vitamin E, aspirin, niacinamide, meldonium, vitamin B1 (thiamine), T3 (triiodothyronine), DNP (2,4-dinitrophenol), PUFA
BScreenshot 2026-06-17 at 21.48.43.png.txt
meldonium + tadalafil = amazing stamina
AScreenshot 2026-06-17 at 21.50.06.png.txt
may sprinkle a bit of Meldonium in and raise the global temperature
Quite liked the guys Nootropic stack I read about a while ago:
- Meldonium
- Emoxypine Succinate (Mexidol)
- Cerebrolysin
- Noopept
- Alpha-GPC
- Memantine
But no clue why someone would run stimulants like Adderall, Desoxyn and God knows what else, and expect all the neurotoxicity to be mitigated with Mexidol, S-Ketamine and Cerebrolysin, more neuroprotection is needed.
Would add:
- HDACi's like Crebinostat or Varinostat (tolerance reversal)
- NACET as superior version of NAC (neuroprotection)
- Bromantane + L-Tyrosine/NALT on hand to replenish Dopamine stores asap and an additional GDNF boost
- Absolute Magnesium megadoses, 1g elemental (Threonate, Glycinate, Chloride etc.)
[reply] not a fan of things that rapidly induce neuroplasticity because they very often mess up top-down control from the prefrontal cortex, it's why i am a bit cautious of Dihexa, low dose probably different tho. Cortexin is nice, but I'd say Pinealon is even more potent for cognition
[reply] i think mexidol, cerebrolysin and perhaps some pinealon would work great
Compounds: meldonium, mexidol (emoxypine succinate), cerebrolysin, noopept, alpha-GPC, memantine, Adderall, Desoxyn, S-ketamine, crebinostat, vorinostat (varinostat), NACET, bromantane, L-tyrosine/NALT, dihexa, cortexin, pinealon, magnesium
- Meldonium
- Emoxypine Succinate (Mexidol)
- Cerebrolysin
- Noopept
- Alpha-GPC
- Memantine
But no clue why someone would run stimulants like Adderall, Desoxyn and God knows what else, and expect all the neurotoxicity to be mitigated with Mexidol, S-Ketamine and Cerebrolysin, more neuroprotection is needed.
Would add:
- HDACi's like Crebinostat or Varinostat (tolerance reversal)
- NACET as superior version of NAC (neuroprotection)
- Bromantane + L-Tyrosine/NALT on hand to replenish Dopamine stores asap and an additional GDNF boost
- Absolute Magnesium megadoses, 1g elemental (Threonate, Glycinate, Chloride etc.)
[reply] not a fan of things that rapidly induce neuroplasticity because they very often mess up top-down control from the prefrontal cortex, it's why i am a bit cautious of Dihexa, low dose probably different tho. Cortexin is nice, but I'd say Pinealon is even more potent for cognition
[reply] i think mexidol, cerebrolysin and perhaps some pinealon would work great
Compounds: meldonium, mexidol (emoxypine succinate), cerebrolysin, noopept, alpha-GPC, memantine, Adderall, Desoxyn, S-ketamine, crebinostat, vorinostat (varinostat), NACET, bromantane, L-tyrosine/NALT, dihexa, cortexin, pinealon, magnesium
when it comes to cognitive enhancement, it should start by enhancing glucose oxidation in the brain, and this should largely be obtained by following Peat's foundation.
but besides that, there are a ton of nootropics that have have enhanced brain glucose metabolism as one of their MOA's
actovegin, meldonium, cerebrolysin, intranasal insulin, mexidol (emoxypine succinate), bromantane/bemethyl come to mind
Compounds: actovegin, meldonium, cerebrolysin, intranasal insulin, mexidol (emoxypine succinate), bromantane/bemethyl
but besides that, there are a ton of nootropics that have have enhanced brain glucose metabolism as one of their MOA's
actovegin, meldonium, cerebrolysin, intranasal insulin, mexidol (emoxypine succinate), bromantane/bemethyl come to mind
Compounds: actovegin, meldonium, cerebrolysin, intranasal insulin, mexidol (emoxypine succinate), bromantane/bemethyl