PQQ (Pyrroloquinoline Quinone)
Category: mitochondria
Mentions
cortxin + 9-me-bc = dopaminergic system restoration
PQQ + ubiquinol = elite preworkout
TTFD + methylated B-vitamins = ridiculous energy
dihexa + nicotine = elite writing & memory
[Reply from BasedBiohacker @BasedBiohacker - Jun 10: epitalon = amazing sleep
modafinil + bromantane = amazing focus
psilocybin + mexidol = amazing charisma
meldonium + tadalafil = amazing stamina
selank + fasopracetam = amazingly calm...]
[Image of a person walking on a glowing path at night in a field]
4:59 PM · Jun 10, 2026 · 15K Views
Compounds: cortxin, 9-ME-BC (9-methyl-beta-carboline), PQQ, ubiquinol, TTFD (thiamine tetrahydrofurfuryl disulfide), methylated B-vitamins, Dihexa, nicotine, epitalon, modafinil, bromantane, psilocybin, mexidol, meldonium, tadalafil, selank, fasopracetam
PQQ + ubiquinol = elite preworkout
TTFD + methylated B-vitamins = ridiculous energy
dihexa + nicotine = elite writing & memory
[Reply from BasedBiohacker @BasedBiohacker - Jun 10: epitalon = amazing sleep
modafinil + bromantane = amazing focus
psilocybin + mexidol = amazing charisma
meldonium + tadalafil = amazing stamina
selank + fasopracetam = amazingly calm...]
[Image of a person walking on a glowing path at night in a field]
4:59 PM · Jun 10, 2026 · 15K Views
Compounds: cortxin, 9-ME-BC (9-methyl-beta-carboline), PQQ, ubiquinol, TTFD (thiamine tetrahydrofurfuryl disulfide), methylated B-vitamins, Dihexa, nicotine, epitalon, modafinil, bromantane, psilocybin, mexidol, meldonium, tadalafil, selank, fasopracetam
_Screenshot 2026-06-17 at 21.49.51.png.txt
take PQQ to maxx out PGC-1a further
AScreenshot 2026-06-17 at 21.50.06.png.txt
300mg TTFD, 1 cap of Thiactive B, 400mg Ubiquinol, 100mg PQQ, 2 grams Shilajit and 5 grams royal jelly
If you believe metabolism is important, it makes NO SENSE to not megadose PQQ.
By increasing the amount of mitochondria you have (through PGC1α activation) you improve across your entire body; hair, heart, fat tissue, liver, brain, skin, muscles literally everywhere.
No surprise it is able to improve cognition, endurance, strength, inflammation, sleep, fat burning and a list of 1000 other things.
50mg a day at least. Go into debt if you have to.
Compounds: PQQ
By increasing the amount of mitochondria you have (through PGC1α activation) you improve across your entire body; hair, heart, fat tissue, liver, brain, skin, muscles literally everywhere.
No surprise it is able to improve cognition, endurance, strength, inflammation, sleep, fat burning and a list of 1000 other things.
50mg a day at least. Go into debt if you have to.
Compounds: PQQ
you want ridiculous energy levels, elite cognitive functioning and more strength/endurance?
train HIIT and use these:
waking up:
1-2g Shilajit
pre workout:
300mg Ubiquinol
100mg PQQ
intraworkout:
1L orange juice
before bed:
10mg K2 MK4
mitochondrial biogenesis
Compounds: shilajit, ubiquinol, PQQ, vitamin K2 (MK-4)
train HIIT and use these:
waking up:
1-2g Shilajit
pre workout:
300mg Ubiquinol
100mg PQQ
intraworkout:
1L orange juice
before bed:
10mg K2 MK4
mitochondrial biogenesis
Compounds: shilajit, ubiquinol, PQQ, vitamin K2 (MK-4)
tried meldonium and thyroid combined, both in a higher dose past few days
brainfog was the result
defo depletes cofactors very quickly
let's see what happens when combined with 200mg CoQ10, an even higher magnesium dose, 20mg PQQ, 600mg benfotiamine, methylated B-complex and maybe some TTFD as well
no I don't know my methylation status, so let's just see what happens
Compounds: meldonium, thyroid (T3), CoQ10, magnesium, PQQ, benfotiamine, methylated B-complex, TTFD
brainfog was the result
defo depletes cofactors very quickly
let's see what happens when combined with 200mg CoQ10, an even higher magnesium dose, 20mg PQQ, 600mg benfotiamine, methylated B-complex and maybe some TTFD as well
no I don't know my methylation status, so let's just see what happens
Compounds: meldonium, thyroid (T3), CoQ10, magnesium, PQQ, benfotiamine, methylated B-complex, TTFD
Humble pre-workout from today:
> Orange juice
> PQQ 40mg
> Benfothiamine 300mg
> Ubiquinone 200mg
> Royal jelly 5g
> Coffee + 8 sugars
> Trenbolone 30mg
They have been a blast lately.
Compounds: PQQ, benfothiamine, ubiquinone, royal jelly, coffee, trenbolone
> Orange juice
> PQQ 40mg
> Benfothiamine 300mg
> Ubiquinone 200mg
> Royal jelly 5g
> Coffee + 8 sugars
> Trenbolone 30mg
They have been a blast lately.
Compounds: PQQ, benfothiamine, ubiquinone, royal jelly, coffee, trenbolone
PQQ lowers inflammation & improves mitochondrial function in clinical study.
Doses of 0.2-0.3 mg / kg:
◇ Showed improvements in antioxidant status (with a single dose)
◇ Reduced IL-6
◇ Slashed CRP
◇ Reduced TCA intermediates
◇ Improved pyruvate / lactate ratio
A molecule found in natto, parsley, green peppers - PQQ acts as a redox exchanger in the cell, meaning it can be an antioxidant against damage or a pro-oxidant for energy production.
[quoting his own earlier thread] The lost longevity vitamin 100-1000X more powerful than vitamin C - Pyrroloquinoline Quinone (PQQ): found in parsley, green tea, kiwi, papaya. PQQ is a redox factor that rapidly eliminates damaging free radicals & supercharges mitochondrial function. Enhances NAD+/NADH ratio, activates sirtuins, stimulates mitochondrial biogenesis, inhibits NF-κB, cofactor for multiple enzymes. Improves lifespan, intestinal permeability / gut dysbiosis, heart failure, neurodegeneration, inflammatory markers, exercise capacity. Might even be an essential nutrient. Safe in studies so far - supplementing at 10+ mg / day.
Compounds: PQQ (cites clinical study — Harris et al. 2013, PMID 24231099)
Doses of 0.2-0.3 mg / kg:
◇ Showed improvements in antioxidant status (with a single dose)
◇ Reduced IL-6
◇ Slashed CRP
◇ Reduced TCA intermediates
◇ Improved pyruvate / lactate ratio
A molecule found in natto, parsley, green peppers - PQQ acts as a redox exchanger in the cell, meaning it can be an antioxidant against damage or a pro-oxidant for energy production.
[quoting his own earlier thread] The lost longevity vitamin 100-1000X more powerful than vitamin C - Pyrroloquinoline Quinone (PQQ): found in parsley, green tea, kiwi, papaya. PQQ is a redox factor that rapidly eliminates damaging free radicals & supercharges mitochondrial function. Enhances NAD+/NADH ratio, activates sirtuins, stimulates mitochondrial biogenesis, inhibits NF-κB, cofactor for multiple enzymes. Improves lifespan, intestinal permeability / gut dysbiosis, heart failure, neurodegeneration, inflammatory markers, exercise capacity. Might even be an essential nutrient. Safe in studies so far - supplementing at 10+ mg / day.
Compounds: PQQ (cites clinical study — Harris et al. 2013, PMID 24231099)
Human crossover trial (n=10): PQQ at 0.2 mg/kg (single dose) and 0.3 mg/kg/day (3 days). Lowered plasma TBARS/malondialdehyde (antioxidant effect, correlated with serum PQQ R=0.74); reduced CRP and IL-6 in all 10 subjects (CRP ~45%); fell lactate:pyruvate ratio (4.5→3.6) and summed urinary TCA intermediates (~15%, fumarate -18%); decreased urinary TMAO. Direct human evidence for PQQ's anti-inflammatory + mitochondrial-metabolic effects. PMID 24231099; open-access full text.
Compounds: pqq
Compounds: pqq