Tadalafil
Category: cardiovascular
Mentions
The 80/20 cognitive enhancement stack that hits hard as FUCK with zero tolerance buildup and zero waste:
- 150 mg armodafinil (cleaner pharmacokinetics than modafinil, longer-lasting wakefulness + deep focus)
- 250 mg citicoline (replenish the depleted stores of the vital neurotransmitter acetylcholine from armodafinil depletion)
- 200 mg caffeine (extra kick, focus, capsule form or just bang black coffee/ espressos all day long)
- 800 mg l-theanine (takes the edge off the stimulating compounds, calm + creative)
- 144 mg magnesium l-threonate (optimizes cognitive health by crossing BBB, helps with sleep quality)
- 2 mg oral pinealon (obliterates brain fog, heightens stress-resistance + focus, helps you sleep deeper)
- 6 mg oral epitalon (resets circadian rhythm despite long-lasting armodafinil, lowers cortisol, amazing for longevity)
you could run this 5 days on, 2 days off pretty much indefinitely without building a tolerance. cycle pinealon and epitalon 30 days on -> 2 months off, then continue as you please.
epitalon in the evening, everything else in the morning (magnesium can also be taken in the evening, but i prefer morning). if you need to prioritize due to $ constraints, remove epi + pine first. honorary mention tadalafil. honorary mention do a damn blood panel and fix whatever is bad first. not medical advice.
sources below, US domestic here. more in this doc (incl. EU, aus etc.): basedbiohacker.any.org/cognitive-enha...
armodafinil: modafinlxl.com/buy/waklert-do...
pinealon: yourprotocol.co/products/pinea...
epitalon: yourprotocol.co/products/epita...
magnesium l-threonate: nootropicsdepot.com/magtein-magnes...
citicoline: nootropicsdepot.com/cognizin-citic...
l-theanine: nootropicsdepot.com/L-theanine-cap...
Compounds: armodafinil, citicoline, caffeine, l-theanine, magnesium l-threonate, pinealon, epitalon, tadalafil
- 150 mg armodafinil (cleaner pharmacokinetics than modafinil, longer-lasting wakefulness + deep focus)
- 250 mg citicoline (replenish the depleted stores of the vital neurotransmitter acetylcholine from armodafinil depletion)
- 200 mg caffeine (extra kick, focus, capsule form or just bang black coffee/ espressos all day long)
- 800 mg l-theanine (takes the edge off the stimulating compounds, calm + creative)
- 144 mg magnesium l-threonate (optimizes cognitive health by crossing BBB, helps with sleep quality)
- 2 mg oral pinealon (obliterates brain fog, heightens stress-resistance + focus, helps you sleep deeper)
- 6 mg oral epitalon (resets circadian rhythm despite long-lasting armodafinil, lowers cortisol, amazing for longevity)
you could run this 5 days on, 2 days off pretty much indefinitely without building a tolerance. cycle pinealon and epitalon 30 days on -> 2 months off, then continue as you please.
epitalon in the evening, everything else in the morning (magnesium can also be taken in the evening, but i prefer morning). if you need to prioritize due to $ constraints, remove epi + pine first. honorary mention tadalafil. honorary mention do a damn blood panel and fix whatever is bad first. not medical advice.
sources below, US domestic here. more in this doc (incl. EU, aus etc.): basedbiohacker.any.org/cognitive-enha...
armodafinil: modafinlxl.com/buy/waklert-do...
pinealon: yourprotocol.co/products/pinea...
epitalon: yourprotocol.co/products/epita...
magnesium l-threonate: nootropicsdepot.com/magtein-magnes...
citicoline: nootropicsdepot.com/cognizin-citic...
l-theanine: nootropicsdepot.com/L-theanine-cap...
Compounds: armodafinil, citicoline, caffeine, l-theanine, magnesium l-threonate, pinealon, epitalon, tadalafil
running this interesting stack for the coming 4-8 weeks or so:
morning
amantadine 100-200mg
royal jelly 5g
tadalafil 5mg
subq selanık 500mcg
epitalon 4mg
vilon 1mg
mexidol 250mg
ALCAR 500mg
mid-day/ afternoon
cerebrolysin 5ml (10 days)
agmatine sulfate 0.5g
evening
guanfacine 2-4mg
magnesium l-threonate 144mg
at need
intranasal insulin 20-60iu (non-modafinil days)
modafinil/armodafinil (100mg max)
NACET 50-100mg
citicoline 250mg
excluded supplements here as my current supp stack is weird to heal my broken foot.
trying something new here, focused on neuroprotection, dopaminergic and executive function optimization, glutamate mitigation, and systemic cellular longevity - not just acute (or even long-term) efficacy.
saving selegiline for the next experiments (the MAO inhibition is too limiting, it would be annoying)
not medical advice.
Compounds: amantadine, royal jelly, tadalafil, selanık (semax or selank), epitalon, vilon, mexidol (emoxypine), ALCAR, cerebrolysin, agmatine sulfate, guanfacine, magnesium l-threonate, intranasal insulin, modafinil, armodafinil, NACET, citicoline, selegiline
morning
amantadine 100-200mg
royal jelly 5g
tadalafil 5mg
subq selanık 500mcg
epitalon 4mg
vilon 1mg
mexidol 250mg
ALCAR 500mg
mid-day/ afternoon
cerebrolysin 5ml (10 days)
agmatine sulfate 0.5g
evening
guanfacine 2-4mg
magnesium l-threonate 144mg
at need
intranasal insulin 20-60iu (non-modafinil days)
modafinil/armodafinil (100mg max)
NACET 50-100mg
citicoline 250mg
excluded supplements here as my current supp stack is weird to heal my broken foot.
trying something new here, focused on neuroprotection, dopaminergic and executive function optimization, glutamate mitigation, and systemic cellular longevity - not just acute (or even long-term) efficacy.
saving selegiline for the next experiments (the MAO inhibition is too limiting, it would be annoying)
not medical advice.
Compounds: amantadine, royal jelly, tadalafil, selanık (semax or selank), epitalon, vilon, mexidol (emoxypine), ALCAR, cerebrolysin, agmatine sulfate, guanfacine, magnesium l-threonate, intranasal insulin, modafinil, armodafinil, NACET, citicoline, selegiline
A lot of people asking about Bromantane
This stuff is CRAZY but works best if you supplement with Tyrosine too, at least 0.5-1g a day
Why? Because Tyrosine is what dopamine is built from. Tyrosine -> L-DOPA -> Dopamine is the process
Uprating your dopamine ceiling without the fuel to build much dopamine will be much less effective
I take 0.5g daily and noticed life changing benefits from bromantane within 2-3 weeks
[Shows a quote tweet from Zygomatic93 - May 15: "MY TOP FIVE HIGHEST ROI BIOHACKS: BROMANTANE - Literally fixes ADHD, TADALAFIL - Vascular health and longevity, epic boners that will blow your foi..."]
9:17 PM · May 15, 2026 · 19.1K Views
Compounds: bromantane, tyrosine, L-DOPA, dopamine, tadalafil
This stuff is CRAZY but works best if you supplement with Tyrosine too, at least 0.5-1g a day
Why? Because Tyrosine is what dopamine is built from. Tyrosine -> L-DOPA -> Dopamine is the process
Uprating your dopamine ceiling without the fuel to build much dopamine will be much less effective
I take 0.5g daily and noticed life changing benefits from bromantane within 2-3 weeks
[Shows a quote tweet from Zygomatic93 - May 15: "MY TOP FIVE HIGHEST ROI BIOHACKS: BROMANTANE - Literally fixes ADHD, TADALAFIL - Vascular health and longevity, epic boners that will blow your foi..."]
9:17 PM · May 15, 2026 · 19.1K Views
Compounds: bromantane, tyrosine, L-DOPA, dopamine, tadalafil
cortxin + 9-me-bc = dopaminergic system restoration
PQQ + ubiquinol = elite preworkout
TTFD + methylated B-vitamins = ridiculous energy
dihexa + nicotine = elite writing & memory
[Reply from BasedBiohacker @BasedBiohacker - Jun 10: epitalon = amazing sleep
modafinil + bromantane = amazing focus
psilocybin + mexidol = amazing charisma
meldonium + tadalafil = amazing stamina
selank + fasopracetam = amazingly calm...]
[Image of a person walking on a glowing path at night in a field]
4:59 PM · Jun 10, 2026 · 15K Views
Compounds: cortxin, 9-ME-BC (9-methyl-beta-carboline), PQQ, ubiquinol, TTFD (thiamine tetrahydrofurfuryl disulfide), methylated B-vitamins, Dihexa, nicotine, epitalon, modafinil, bromantane, psilocybin, mexidol, meldonium, tadalafil, selank, fasopracetam
PQQ + ubiquinol = elite preworkout
TTFD + methylated B-vitamins = ridiculous energy
dihexa + nicotine = elite writing & memory
[Reply from BasedBiohacker @BasedBiohacker - Jun 10: epitalon = amazing sleep
modafinil + bromantane = amazing focus
psilocybin + mexidol = amazing charisma
meldonium + tadalafil = amazing stamina
selank + fasopracetam = amazingly calm...]
[Image of a person walking on a glowing path at night in a field]
4:59 PM · Jun 10, 2026 · 15K Views
Compounds: cortxin, 9-ME-BC (9-methyl-beta-carboline), PQQ, ubiquinol, TTFD (thiamine tetrahydrofurfuryl disulfide), methylated B-vitamins, Dihexa, nicotine, epitalon, modafinil, bromantane, psilocybin, mexidol, meldonium, tadalafil, selank, fasopracetam
the meldonium + tadalafil + bromantane + modafinil stack is STUPID GOOD for cognitive and performance enhancement:
→ tadalafil increases cerebral blood flow; more oxygen and nutrients reaching your brain
→ meldonium shifts neurons to use glucose more efficiently under that increased delivery
→ modafinil drives acute focus and wakefulness on top of the already optimized foundation
→ bromantane upregulates tyrosine hydroxylase so your dopamine production capacity actually builds instead of depleting
blood flow → neural efficiency → cognitive output → neurotransmitter sustainability
four different entry points all converging on a beautiful path of pure fucking output
and then you just munch on skittles and gummy bears as your carb source throughout the day as meldonium literally shifts your metabolism toward glucose utilization, also incredibly important to hydrate with electrolytes throughout the day as glucose metabolization uses up massive amounts of magnesium and potassium
you literally become a well-oiled pharmacological MACHINE running on fucking candy and all-ends optimization
add pinealon and epitalon for sleep and you might get the midas touch
not medical advice, and definitely start on low doses (can be heavy on the cardiovascular system for some) but this is the schedule i follow
- meldonium sublingual 500-1000 mg 6 weeks on, several months off (supplement l-carnitine when you go off)
- modafinil 100-200 mg
- bromantane sublingual 50 mg (daily)
- tadalafil 5 mg daily
again, not medical advice... this is high level shit
all sources and info here: basedbiohacker.any.org/cognitive-enha...
us sources linked below (comment if you know domestic us meldonium source)
Compounds: meldonium, tadalafil, bromantane, modafinil, pinealon, epitalon, l-carnitine, magnesium, potassium
→ tadalafil increases cerebral blood flow; more oxygen and nutrients reaching your brain
→ meldonium shifts neurons to use glucose more efficiently under that increased delivery
→ modafinil drives acute focus and wakefulness on top of the already optimized foundation
→ bromantane upregulates tyrosine hydroxylase so your dopamine production capacity actually builds instead of depleting
blood flow → neural efficiency → cognitive output → neurotransmitter sustainability
four different entry points all converging on a beautiful path of pure fucking output
and then you just munch on skittles and gummy bears as your carb source throughout the day as meldonium literally shifts your metabolism toward glucose utilization, also incredibly important to hydrate with electrolytes throughout the day as glucose metabolization uses up massive amounts of magnesium and potassium
you literally become a well-oiled pharmacological MACHINE running on fucking candy and all-ends optimization
add pinealon and epitalon for sleep and you might get the midas touch
not medical advice, and definitely start on low doses (can be heavy on the cardiovascular system for some) but this is the schedule i follow
- meldonium sublingual 500-1000 mg 6 weeks on, several months off (supplement l-carnitine when you go off)
- modafinil 100-200 mg
- bromantane sublingual 50 mg (daily)
- tadalafil 5 mg daily
again, not medical advice... this is high level shit
all sources and info here: basedbiohacker.any.org/cognitive-enha...
us sources linked below (comment if you know domestic us meldonium source)
Compounds: meldonium, tadalafil, bromantane, modafinil, pinealon, epitalon, l-carnitine, magnesium, potassium
a few compounds that make natty boys look RETARDED
- bromantane
- epitalon
- meldonium
- pinealon
- royal jelly
- low dose tadalafil
[Image shows muscular bald older man]
[Attached quote from limitlesstack @limitlesstack - Feb 22: "I am a nootropic combination expert. you want executive function? you want neuroplasticity? you want to finish that 6-month project in one weekend? you want to lift mood and crush depression?..."]
5:27 PM · May 25, 2026 · 37.5K Views
Compounds: bromantane, epitalon, meldonium, pinealon, royal jelly, tadalafil
- bromantane
- epitalon
- meldonium
- pinealon
- royal jelly
- low dose tadalafil
[Image shows muscular bald older man]
[Attached quote from limitlesstack @limitlesstack - Feb 22: "I am a nootropic combination expert. you want executive function? you want neuroplasticity? you want to finish that 6-month project in one weekend? you want to lift mood and crush depression?..."]
5:27 PM · May 25, 2026 · 37.5K Views
Compounds: bromantane, epitalon, meldonium, pinealon, royal jelly, tadalafil
BScreenshot 2026-06-17 at 21.47.45.png.txt
stuff i have coming in right now: ... more bromantane, more tadalafil, more modvigil, more waklert
BScreenshot 2026-06-17 at 21.48.33.png.txt
A TIER: tadalafil: PDE5 inhibitor improving cerebral blood flow and vascular optimization systemically
BScreenshot 2026-06-17 at 21.48.43.png.txt
meldonium + tadalafil = amazing stamina
have low energy and no supplement is helping? vilon
can't study and no supplement is helping? tak-653
can't have fun and no supplement is helping? psilocybin
can't focus and no supplement is helping? modafinil
you're stupid and no supplement is helping? dihexa
can't sleep and no supplement is helping? silexan
weak wood and no supplement is helping? tadalafil
the answer is always just deeper down the rabbit hole
[thread replies] brain fog? → bpc-157 fix your gut. procrastination? → cerebrolysin
Compounds: vilon, tak-653, psilocybin, modafinil, dihexa, silexan, tadalafil, bpc-157, cerebrolysin
can't study and no supplement is helping? tak-653
can't have fun and no supplement is helping? psilocybin
can't focus and no supplement is helping? modafinil
you're stupid and no supplement is helping? dihexa
can't sleep and no supplement is helping? silexan
weak wood and no supplement is helping? tadalafil
the answer is always just deeper down the rabbit hole
[thread replies] brain fog? → bpc-157 fix your gut. procrastination? → cerebrolysin
Compounds: vilon, tak-653, psilocybin, modafinil, dihexa, silexan, tadalafil, bpc-157, cerebrolysin