TAK-653
Category: nootropics
Mentions
you can just take noots and stims and be smarter than everyone else
- modafinil (wakefulness + focus)
- cerebrolysin (recovery + cognition)
- crebinostat (literal photographic memory)
- piracetam
- IN insulin (cognition + recovery)
- dextroamphetamine (focus + memory)
- pinealon (recovery + sleep)
- tropisetron (calm focus)
- TAK-653
- guanfacine (non-stim)
- Chlorgyline (MAO-A)
- Usmarapride (memory)
- KW-6365
- Dihexa (low dose - recovery)
- bromantane
- CE-123 (modafinil analogue)
- methylphenidate (focus)
- Menthol (anxiolytic)
the list could go on
life is not a drug tested sport - if you dont enhance yourself your competition will and you will get left behind
Compounds: modafinil, cerebrolysin, crebinostat, piracetam, intranasal insulin, dextroamphetamine, pinealon, tropisetron, TAK-653, guanfacine, Chlorgyline, usmarapride, KW-6365, Dihexa, bromantane, CE-123, methylphenidate, menthol
- modafinil (wakefulness + focus)
- cerebrolysin (recovery + cognition)
- crebinostat (literal photographic memory)
- piracetam
- IN insulin (cognition + recovery)
- dextroamphetamine (focus + memory)
- pinealon (recovery + sleep)
- tropisetron (calm focus)
- TAK-653
- guanfacine (non-stim)
- Chlorgyline (MAO-A)
- Usmarapride (memory)
- KW-6365
- Dihexa (low dose - recovery)
- bromantane
- CE-123 (modafinil analogue)
- methylphenidate (focus)
- Menthol (anxiolytic)
the list could go on
life is not a drug tested sport - if you dont enhance yourself your competition will and you will get left behind
Compounds: modafinil, cerebrolysin, crebinostat, piracetam, intranasal insulin, dextroamphetamine, pinealon, tropisetron, TAK-653, guanfacine, Chlorgyline, usmarapride, KW-6365, Dihexa, bromantane, CE-123, methylphenidate, menthol
if you want focus + a drug-like high and don't care about the consequences take adderall
if you want focus + stimulation without the euphoria and comedown take modafinil
if you want just focus without stimulation take tak-653 or guanfacine
if you just want smooth focus remove all external dopamine from your life and take nicotine
[Image shows a large glowing eye with purple hues]
7:31 PM · May 4, 2026 · 18.2K Views
Compounds: adderall (amphetamine), modafinil, TAK-653, guanfacine, nicotine
if you want focus + stimulation without the euphoria and comedown take modafinil
if you want just focus without stimulation take tak-653 or guanfacine
if you just want smooth focus remove all external dopamine from your life and take nicotine
[Image shows a large glowing eye with purple hues]
7:31 PM · May 4, 2026 · 18.2K Views
Compounds: adderall (amphetamine), modafinil, TAK-653, guanfacine, nicotine
MScreenshot 2026-06-17 at 21.47.40.png.txt
perfect mental enhancement stack for sleep deprivation: ISRIB, cerebrolysin, intranasal insulin, nebivolol, tak-653, magnesium-l-threonate
BScreenshot 2026-06-17 at 21.47.45.png.txt
stuff i have coming in right now: bemethyl, tesofensine, BAM-15, dihexa, pregnenolone, thiamine TTFD, saltorexant, tak-653, vesugen, vilon, nsi-189, pri-8-53, gb-115, acd856, coluracetam
MScreenshot 2026-06-17 at 21.47.50.png.txt
stack that made researching a lot of fun: 3000mg Magtein, 40IU IN insulin, 5mg IN dihexa, 4mg TAK-653, 5g royal jelly, 200mg benfothiamine
BScreenshot 2026-06-17 at 21.47.56.png.txt
if i was a student... i'd just use tak-653 and a medium dose of modafinil. tak-653 acts as an AMPA receptor potentiator, speeding up synaptic transmission in the brain, increasing synaptic plasticity, BDNF release
have low energy and no supplement is helping? vilon
can't study and no supplement is helping? tak-653
can't have fun and no supplement is helping? psilocybin
can't focus and no supplement is helping? modafinil
you're stupid and no supplement is helping? dihexa
can't sleep and no supplement is helping? silexan
weak wood and no supplement is helping? tadalafil
the answer is always just deeper down the rabbit hole
[thread replies] brain fog? → bpc-157 fix your gut. procrastination? → cerebrolysin
Compounds: vilon, tak-653, psilocybin, modafinil, dihexa, silexan, tadalafil, bpc-157, cerebrolysin
can't study and no supplement is helping? tak-653
can't have fun and no supplement is helping? psilocybin
can't focus and no supplement is helping? modafinil
you're stupid and no supplement is helping? dihexa
can't sleep and no supplement is helping? silexan
weak wood and no supplement is helping? tadalafil
the answer is always just deeper down the rabbit hole
[thread replies] brain fog? → bpc-157 fix your gut. procrastination? → cerebrolysin
Compounds: vilon, tak-653, psilocybin, modafinil, dihexa, silexan, tadalafil, bpc-157, cerebrolysin
Anyone tried ACD856, TAK-653 or BPN14770?
ACD856 (Trk/BDNF positive allosteric modulator): ~10mg/day, user reported tripled motivation/mood, reduced rumination/anxiety, lightness and focus; effects faded toward subtle after ~a month; cycle it. Source: Everychem.
TAK-653 (AMPA modulator): used for weeks, zero side effects, better mood and focus especially stacked with Semax and Bromantane; good non-stimulant ADHD option; timing not critical.
BPN14770 (PDE4D inhibitor): ~40-90mg once or twice daily, no insomnia/stimulant feel, but no clear recall/memory benefit vs racetams for one user.
Compounds: ACD856, TAK-653, BPN14770, Semax, Bromantane
ACD856 (Trk/BDNF positive allosteric modulator): ~10mg/day, user reported tripled motivation/mood, reduced rumination/anxiety, lightness and focus; effects faded toward subtle after ~a month; cycle it. Source: Everychem.
TAK-653 (AMPA modulator): used for weeks, zero side effects, better mood and focus especially stacked with Semax and Bromantane; good non-stimulant ADHD option; timing not critical.
BPN14770 (PDE4D inhibitor): ~40-90mg once or twice daily, no insomnia/stimulant feel, but no clear recall/memory benefit vs racetams for one user.
Compounds: ACD856, TAK-653, BPN14770, Semax, Bromantane